Methods and Results The cardiac stem/progenitor cells from adult mice were seeded at low
density in serum-free medium. The colonies thus obtained were expanded separately and …

Background Myocardial infarction remains the leading cause of mortality in developed
countries despite recent advances in its prevention and treatment. Regenerative therapies …

In the past few years it has been established that the heart contains a reservoir of stem and
progenitor cells. These cells are positive for various stem/progenitor cell markers (Kit, Sca-1 …

Rationale: Multiple progenitors derived from the heart and bone marrow (BM) have been
used for cardiac repair. Despite this, not much is known about the molecular identity and …

The adult heart contains reservoirs of progenitor cells that express embryonic and stem cell-
related antigens. While these antigenically-purified cells are promising candidates for …

Objectives: The goal of this study is to characterize resident cardiac stem cells (CSCs) and
investigate their therapeutic efficacy in myocardial infarction by molecular imaging methods …

Resident cardiac stem cells (CSCs) are characterized by their capacity to self-renew in
culture, and are multipotent for forming normal cell types in hearts. CSCs were originally …

Cardiac progenitor/stem cells in adult hearts represent an attractive therapeutic target for
heart regeneration, though (inter)-relationships among reported cells remain obscure. Using …

Cardiac stem cell‐like populations exist in adult hearts, and their roles in cardiac repair
remain to be defined. Sca‐1 is an important surface marker for cardiac and other somatic …

Rationale: Dual cell transplantation of cardiac progenitor cells (CPCs) and mesenchymal
stem cells (MSCs) after infarction improves myocardial repair and performance in large …