Processing of olfactory information is modulated by centrifugal projections from cortical
areas, yet their behavioral relevance and underlying neural mechanisms remain unclear in …

Processing of sensory information is substantially shaped by centrifugal, or feedback,
projections from higher cortical areas, yet the functional properties of these projections are …

Odor information arrives first in the main olfactory bulb and is then broadcasted to the
olfactory cortices and striatum. Downstream regions have unique cellular and connectivity …

In the olfactory system, the olfactory cortex sends glutamatergic projections back to the first
stage of olfactory processing, the olfactory bulb (OB). Such corticofugal excitatory circuits—a …

Serving as an integral node for cognitive processing and value‐based decision‐making, the
orbitofrontal cortex (OFC) plays a multifaceted role in associative learning and reward …

Animals have evolved innate responses to cues including social, food, and predator odors.
In the natural environment, animals are faced with choices that involve balancing risk and …

Interconnections between the olfactory bulb and the amygdala are a major pathway for
triggering strong behavioral responses to a variety of odorants. However, while this broad …

Cholinergic modulation of central circuits is associated with active sensation, attention, and
learning, yet the neural circuits and temporal dynamics underlying cholinergic effects on …

The olfactory cortex encompasses several anatomically distinct regions each hypothesized
to provide differential representation and processing of specific odors. Studies exploring …

Sensory information is selectively or non-selectively enhanced and inhibited in the brain, but
it remains unclear whether and how this occurs at the most peripheral level. Using in vivo …