Plasma homocysteine levels are not increased in murine models of Alzheimer's disease

D Santiard-Baron, J Aupetit, N Janel - Neuroscience research, 2005 - Elsevier
Alzheimer's disease (AD) patients tend to have increased plasma levels of homocysteine.
However, it is unclear whether abnormality in homocysteine levels is a primary cause of …

Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid β peptide levels

J Pacheco-Quinto, EBR de Turco, S DeRosa… - Neurobiology of …, 2006 - Elsevier
Recent epidemiological and clinical data suggest that elevated serum homocysteine levels
may increase the risk of developing Alzheimer's disease (AD), but the underlying …

Genetic influence of plasma homocysteine on Alzheimer's disease

T Roostaei, D Felsky, A Nazeri, PL De Jager… - Neurobiology of …, 2018 - Elsevier
Observational studies have consistently reported elevated plasma homocysteine as a risk
factor for Alzheimer's disease (AD). However, results from clinical trials of homocysteine …

Plasma homocysteine levels and risk of Alzheimer disease

JA Luchsinger, MX Tang, S Shea, J Miller, R Green… - Neurology, 2004 - AAN Enterprises
Objective: To explore the association between high homocysteine levels and risk of
Alzheimer disease (AD) in the Washington Heights-Inwood Columbia Aging Project …

The association between homocysteine and memory in older adults

ME Nelson, R Andel, Z Nedelska… - Journal of …, 2021 - content.iospress.com
Background: Identifying modifiable risk factors for cognitive decline can reduce burden of
dementia. Objective: We examined whether homocysteine was associated with memory …

[PDF][PDF] Plasma homocysteine: a new risk factor for Alzheimer's disease?

EH Mizrahi, DW Jacobsen, RP Friedland - IMAJ-RAMAT GAN-, 2002 - academia.edu
Dementia is a common and devastating public health problem, affecting an estimated
5±10% of individuals over the age of 65 [1]. Two pathologically distinct subtypes of …

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

S Seshadri, A Beiser, J Selhub… - New England journal …, 2002 - Mass Medical Soc
Background In cross-sectional studies, elevated plasma homocysteine levels have been
associated with poor cognition and dementia. Studies of newly diagnosed dementia are …

Relation of plasma homocysteine to plasma amyloid beta levels

JA Luchsinger, MX Tang, J Miller, R Green… - Neurochemical …, 2007 - Springer
Background Elevated plasma homocysteine and amyloid β (Aβ) have been associated with
Alzheimer's disease (AD). We investigated the cross-sectional association between these …

Homocysteine and brain atrophy on MRI of non‐demented elderly

T den Heijer, SE Vermeer, R Clarke, M Oudkerk… - Brain, 2002 - academic.oup.com
Patients with Alzheimer's disease have higher plasma homocysteine levels than controls,
but it is uncertain whether higher plasma homocysteine levels are involved in the early …

Homocysteine as a predictor of cognitive decline in Alzheimer's disease

A Oulhaj, H Refsum, H Beaumont… - … journal of geriatric …, 2010 - Wiley Online Library
Objective Moderately elevated levels of plasma total homocysteine are associated with an
increased risk of developing Alzheimer's disease. We have tested whether baseline …