A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42
M Fukuoka, S Suetsugu, H Miki, K Fukami… - The Journal of cell …, 2001 - rupress.org
We identified a novel adaptor protein that contains a Src homology (SH) 3 domain, SH3
binding proline-rich sequences, and a leucine zipper-like motif and termed this protein …
binding proline-rich sequences, and a leucine zipper-like motif and termed this protein …
Identification of another actin-related protein (Arp) 2/3 complex binding site in neural Wiskott-Aldrich syndrome protein (N-WASP) that complements actin …
Neural Wiskott-Aldrich syndrome protein (N-WASP) is an essential regulator of actin
cytoskeleton formation via its association with the actin-related protein (Arp) 2/3 complex. It …
cytoskeleton formation via its association with the actin-related protein (Arp) 2/3 complex. It …
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate
R Rohatgi, HH Ho, MW Kirschner - The Journal of cell biology, 2000 - rupress.org
Neuronal Wiskott-Aldrich Syndrome protein (N-WASP) transmits signals from Cdc42 to the
nucleation of actin filaments by Arp2/3 complex. Although full-length N-WASP is a weak …
nucleation of actin filaments by Arp2/3 complex. Although full-length N-WASP is a weak …
GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex
MF Carlier, P Nioche, I Broutin-L'Hermite… - Journal of Biological …, 2000 - ASBMB
Proteins of the Wiskott-Aldrich Syndrome protein (WASp) family connect signaling pathways
to the actin polymerization-driven cell motility. The ubiquitous homolog of WASp, N-WASp, is …
to the actin polymerization-driven cell motility. The ubiquitous homolog of WASp, N-WASp, is …
CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family
HYH Ho, R Rohatgi, L Ma… - Proceedings of the …, 2001 - National Acad Sciences
The Neuronal Wiskott–Aldrich syndrome protein (N-WASP) has emerged as a central
regulator of the actin cytoskeleton with abilities to integrate multiple upstream signal inputs …
regulator of the actin cytoskeleton with abilities to integrate multiple upstream signal inputs …
Nck and phosphatidylinositol 4, 5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway
R Rohatgi, P Nollau, HYH Ho, MW Kirschner… - Journal of Biological …, 2001 - ASBMB
The Wiskott-Aldrich syndrome protein (WASP) and its relative neural WASP (N-WASP)
regulate the nucleation of actin filaments through their interaction with the Arp2/3 complex …
regulate the nucleation of actin filaments through their interaction with the Arp2/3 complex …
Interaction of HSP90 to N‐WASP leads to activation and protection from proteasome‐dependent degradation
SJ Park, S Suetsugu, T Takenawa - The EMBO Journal, 2005 - embopress.org
Neural Wiskott–Aldrich syndrome protein (N‐WASP) regulates reorganization of the actin
cytoskeleton through activation of the Arp2/3 complex. Here, we show that heat shock …
cytoskeleton through activation of the Arp2/3 complex. Here, we show that heat shock …
Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP
GOC Cory, R Cramer, L Blanchoin, AJ Ridley - Molecular cell, 2003 - cell.com
Wiskott-Aldrich syndrome protein (WASP) and neural (N)-WASP regulate dynamic actin
structures through the ability of their VCA domains to bind to and stimulate the actin …
structures through the ability of their VCA domains to bind to and stimulate the actin …
Essential role of neural Wiskott-Aldrich syndrome protein in neurite extension in PC12 cells and rat hippocampal primary culture cells
Neural Wiskott-Aldrich syndrome protein (N-WASP) is an actin-regulating protein that
induces filopodium formation downstream of Cdc42. It has been shown that filopodia …
induces filopodium formation downstream of Cdc42. It has been shown that filopodia …
Interactions of isolated C-terminal fragments of neural Wiskott-Aldrich syndrome protein (N-WASP) with actin and Arp2/3 complex
JF Gaucher, C Maugé, D Didry, B Guichard… - Journal of Biological …, 2012 - ASBMB
Wiskott-Aldrich syndrome proteins (WASP) are a family of proteins that all catalyze actin
filament branching with the Arp2/3 complex in a variety of actin-based motile processes. The …
filament branching with the Arp2/3 complex in a variety of actin-based motile processes. The …