Cigarette smoking is highly destructive to individuals and society, and is moderately
heritable. We completed a genomewide linkage scan to map loci increasing risk for cigarette …

BACKGROUND: Alcohol dependence (AD) is costly to societies worldwide, moderately
heritable, and genetically complex. Risk loci in several populations have been identified with …

BACKGROUND: A genetic contribution to smoking behavior is well-established. To identify
loci that increase the risk for smoking behavior, many genome-wide linkage scans have …

We conducted a genomewide linkage screen of a simple heavy-smoking quantitative trait,
the maximum number of cigarettes smoked in a 24-h period, using two independent …

Nicotine withdrawal (NW) is both an important contributor to difficulty quitting cigarettes and
because of mood-related withdrawal symptoms a problem of particular relevance to …

Genome-wide model free linkage analysis was conducted for nicotine dependence and
tobacco use phenotypes in 607 members of 158 nuclear families consisting of at least two …

Association genome scanning can identify markers for the allelic variants that contribute to
vulnerability to complex disorders, including alcohol dependence. To improve the power …

Genome-wide association studies (GWAS) currently represent the most systematic approach
to genetic research into complex disorders. They can detect associations of common …

The identification and exploration of genetic loci that influence smoking behaviors have
been conducted primarily in populations of the European ancestry. Here we report results of …

The present study searched for replicable risk genomic regions for alcohol and nicotine co‐
dependence using a genome‐wide association strategy. The data contained a total of 3,143 …