Pathologic calcification of implants is a detrimental condition that can severely impact device
performance and ultimately lead to implant failure. Although calcification affects a wide …

Ectopic or dystrophic calcification promotes premature implant and medical device failure.
This chapter summarizes the various mechanisms of calcification proposed in the literature …

Calcification is one of the most common issues that arise concerning biocompatibility, known
to affect many systems in the body. It is often associated with an increase in free phosphate …

Deposition of calcium-containing apatite mineral occurs widely in association with
cardiovascular and noncardiovascular medical devices and biomaterials, is the leading …

Calcification of cardiovascular prosthetic implants is a common and important problem. This
review provides an update based upon the Conference on Cardiovascular Implant …

Improvements in healthcare yields a rise in numbers of elderly people, which in turn
increases the demand for healthcare among this population. Today, some 300 000 heart …

Bioprostheses, composed of chemically treated animal tissue and termed heterografts or
xenografts, are the most widely used type of substitute heart valve. Their major limitation is …

Calcification is still a major cause of failure of implantable biomaterials. A fast and reliable in
vitro model could contribute to the study of its mechanisms and to testing different …

The calcification of polymeric materials in long-term medical implants such is cardiac assist
devices and artificial hearts is increasingly being recognized. Calcification is a complex …

The use of bioprosthetic valves fabricated from fixed heterograft tissue (porcine aortic valves
or bovine pericardium) in heart valve replacement surgery is limited because of calcification …