[HTML][HTML] Understanding the role of neutrophils in acute respiratory distress syndrome

SC Yang, YF Tsai, YL Pan, TL Hwang - Biomedical Journal, 2021 - Elsevier
… The severity and mortality of COVID-19 ARDS are correlated to higher neutrophil counts
and NET level [29,101]. NETs play a significant role in producing a cytokine storm [102,103]. …

Ferritin triggers neutrophil extracellular trap-mediated cytokine storm through Msr1 contributing to adult-onset Still's disease pathogenesis

J Jia, M Wang, J Meng, Y Ma, Y Wang, N Miao… - Nature …, 2022 - nature.com
… Collectively, our findings demonstrate an essential role of ferritin in NET-mediated
cytokine storm, and suggest that targeting NETs or Msr1 may benefit AOSD patients. …

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
Cytokines play a vital role throughout the four stages of … the specific cytokine that has been
secreted, their role can be to … such as macrophages and neutrophils, though endothelial cells …

Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis

MC Cesta, M Zippoli, C Marsiglia… - European Journal of …, 2023 - Wiley Online Library
… addresses the critical role of the polymorphonuclear neutrophils and the inflammatory
cytokine storm caused by an accumulation of high plasma levels of inflammatory cytokines [15]. …

Cytokine storm syndrome in SARS-CoV-2 infections: a functional role of mast cells

B Hafezi, L Chan, JP Knapp, N Karimi, K Alizadeh… - Cells, 2021 - mdpi.com
cytokines and eventually the development of cytokine storm … In this review, we present
evidence that a cytokine response … cause the development of cytokine storm syndrome. We also …

Comparing the cytokine storms of COVID-19 and pandemic influenza

LM Pacheco-Hernández… - … interferon & cytokine …, 2022 - liebertpub.com
… An important cytokine for antiviral defenses that plays a pathogenic role during severe …
Finally, IL-6 favors neutrophil recruitment and B cell differentiation. However, its excessive …

An enlightening role for cytokine storm in coronavirus infection

Z Zhao, Y Wei, C Tao - Clinical Immunology, 2021 - Elsevier
cytokine storm are heterogeneous but infection is the most frequent cause clinically [12]. In
graft versus host disease cytokine storm is … as infiltration of neutrophils and macrophages into …

[HTML][HTML] Understanding the roles of cytokines and neutrophil activity and neutrophil apoptosis in the protective versus deleterious inflammatory response in pneumonia

J Bordon, S Aliberti, R Fernandez-Botran… - International Journal of …, 2013 - Elsevier
… the modulation of neutrophil apoptosis. On the other hand, a cytokine storm results in a …
This review examines the role of cytokines, neutrophil activity, and neutrophil apoptosis in the …

Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …

A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
cytokine storm. Both local tissue inflammation and the cytokine storm play a fundamental
role in the … The infiltration of macrophages and neutrophils in the lung tissues of the MERS-CoV-…

Neutrophils in COVID-19: not innocent bystanders

E McKenna, R Wubben, JM Isaza-Correa… - Frontiers in …, 2022 - frontiersin.org
… emerging data on the roles of neutrophils in the … neutrophils can produce cytokines such
as IL-1β, IL-6, TNF-α, MIF, IL-12, TGF-β, IL-21, IL-23 and IL-27, contributing to a cytokine storm