The cytokine storm in COVID-19: the strongest link to morbidity and mortality in the current epidemic

M Basheer, E Saad, N Assy - COVID, 2022 - mdpi.com
Cytokine Storm in Immunodeficient Patients The uncontrolled production of cytokines, ie, the
cytokine storm, has the strongest link … The cytokine storm is usually a warning sign of COVID-…

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… Indeed elevated sC5b-9 (a marker of endothelial dysfunction) correlated with increased
CXCL8 (as well as IL-6 and TNF-α) levels, suggesting a link between CXCL8 levels and innate …

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
… specific pathologies reflect the strong alterations observed in … investigation of the cytokine
storms during SARS-CoV-2 … A viruses, linking shared or specific changing cytokines and …

Cytokine storms in infectious diseases

JR Teijaro - Seminars in immunopathology, 2017 - Springer
… Despite a definitive link of cytokine and chemokine levels … to quell the pathology associated
with cytokine storm. In fact, the … Despite this strong correlation, no effective therapies targeting …

Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
… and mononuclear cells may be the key link of cytokine storm in COVID-19 (45). Moreover,
the activation of monocytes may suggest that the cytokine storm in COVID-19 is closely related …

Dynamics of a cytokine storm

HH Yiu, AL Graham, RF Stengel - 2012 - journals.plos.org
… are grouped according to their distance from each other, with the height of the links indicating
strong effect on the other cytokines. Eliminating IL12 does not significantly impact the other …

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
… as the increase in specific cytokine production, and which can be linked to viral clearance, …
Nevertheless, despite strong evidence of a cytokine storm in many severe acute infections, …

Cytokine storm signature in patients with moderate and severe COVID-19

O Kalinina, A Golovkin, E Zaikova, A Aquino… - International Journal of …, 2022 - mdpi.com
… The strongest discriminating factors … linked with COVID-19 severity [7]. Thus, we found that
the increased concentrations of pro-inflammatory IL-6, IP-10, and TNF α were closely linked

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
… Available evidence indicate that the so called “cytokine storm” an uncontrolled over-… of the
chemokine/chemokine-receptor system in the cytokine storm related to SARS-CoV-2 infection. …

Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
… There was a strong evidence to suggest the possibility of a publication bias among studies
… These cytokines and chemokines have also been linked to extrapulmonary complications of …