… Although there are multiple tools that enable its detection from Nanoporesequencing, … methylation from Nanoporesequencing using individual reads, control mixtures of methylated and …
Q Gouil, A Keniry - Essays in biochemistry, 2019 - portlandpress.com
… in detecting base modifications in native DNA and highlight the respective strengths and weaknesses of PacBio and Nanoporesequencing for this application. Although analysing …
A Tourancheau, EA Mead, XS Zhang, G Fang - Nature methods, 2021 - nature.com
… In this work, we observed that a nanoporesequencing signal displays complex … methylation events of the same type. To enable nanoporesequencing for broadly applicable methylation …
J Zhang, S Xie, J Xu, H Liu, S Wan - Frontiers in Genetics, 2021 - frontiersin.org
… advances of nanoporesequencing techniques for detecting methylation modifications and … The emergence of nanoporesequencing analysis has enabled direct methylation readout …
… Nanopore flowcells and signal data formats. We perform whole-genome Nanoporesequencing of the NIH3T3 cell line (a widely used mouse reference cell line for methylation studies) …
… , we use nanoporesequencing to evaluate CpG methylation and … We performed nanopore sequencing of nucleosome … Long-read sequencing makes it possible to robustly assign reads …
… detect DNA methylation states from Nanoporesequencing reads. Testing on Nanopore reads … level on detecting 6 mA and 5mC methylation states comparing to previous hidden Markov …
… Nanoporesequencing for epidemiology by performing a comparison with DNA methylation … -Cas9 targeted sequencing approach in concert with Nanoporesequencing to profile DNA …
LP Kuschel, J Hench, S Frank, IB Hench… - Neuropathology and …, 2023 - Wiley Online Library
… In conclusion, nanoporesequencing allows robust and rapid methylation-based classification across the full spectrum of brain tumours. Platform-specific confidence scores facilitate …