Current insights and future prospects for targeting IL-17 to treat patients with systemic lupus erythematosus

T Koga, K Ichinose, A Kawakami… - Frontiers in …, 2021 - frontiersin.org
… -17-targeted therapies for autoimmune diseases, including SLE, and their future prospects.
… CaMK4 is a multifunctional serine/threonine kinase that regulates pro-inflammatory cytokines

Immune responses to human fungal pathogens and therapeutic prospects

MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
pro-inflammatory cytokines 33 . Correspondingly, genetic polymorphisms in NLRP3, SIGLEC15,
IDO1 and other genes that augment the vaginal inflammatory milieu are associated with …

Cytokines-their functional roles and prospective applications in veterinary practice: A review

K Dhama, M Mahendran, RS Chauhan… - Journal of Immunology …, 2008 - indianjournals.com
… practical implementation, for better prospects in the field of animal disease prevention and
cytokines and soluble cytokine receptors offers the prospect of specific clinical therapies to …

Blood platelets and sepsis pathophysiology: a new therapeutic prospect in critical ill patients?

A Dewitte, S Lepreux, J Villeneuve, C Rigothier… - Annals of intensive …, 2017 - Springer
Pro-inflammatory cytokines released by platelets can also activate the coagulation cascade
at various steps [86]. Conversely, the activation of coagulation by platelets generates a …

Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects

H Khan, H Ullah, SM Nabavi - Food and Chemical Toxicology, 2019 - Elsevier
… Curcumin suppresses proinflammatory cytokines and thus inhibiting inflammatory cascade.
It inhibit NF-kB (transcription factor) resulting in suppression of a number of proinflammatory

Cytokine therapy in dermatology

K Asadullah, W Sterry, U Trefzer - Experimental dermatology, 2002 - Wiley Online Library
… Here we would like to give an overview about the current stage of cytokine therapy and the
prospects for dermatological indications. The terminology and immunobiology of cytokines

[HTML][HTML] Role of inflammatory response in liver diseases: Therapeutic strategies

JA Del Campo, P Gallego, L Grande - World journal of hepatology, 2018 - ncbi.nlm.nih.gov
… 1 and induce the maturation and secretion of important proinflammatory cytokines such
as IL-1β and IL-18. Cytokines act directly against the damage and infection of the liver tissue[18]. …

Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components

H Martin - … Research/Fundamental and Molecular Mechanisms of …, 2009 - Elsevier
… Not only was secretion of the pro-inflammatory cytokines, IL6 and IL8, reduced by these …
the expression of TNF-α, a pro-inflammatory cytokine and marker of inflammation, and increased …

Therapeutic prospects for Th-17 cell immune storm syndrome and neurological symptoms in COVID-19: thiamine efficacy and safety, in-vitro evidence and …

V Vatsalya, F Li, J Frimodig, KS Gala, S Srivastava… - medRxiv, 2020 - medrxiv.org
… We hypothesized that countering the cytokine storm with thiamine may have therapeutic
efficacy in lowering the Th17 cell proinflammatory response. We used an in vitro study and …

Prospects of apoptotic cell-based therapies for transplantation and inflammatory diseases

P Saas, S Kaminski, S Perruche - Immunotherapy, 2013 - Taylor & Francis
proinflammatory cytokine secretion by TLR stimulation (Table 1) . A decrease of proinflammatory
cytokine … can be a direct effect on proinflammatory cytokine genes independent of IL-10 …