Th17‐associated cytokines as a therapeutic target for steroid‐insensitive asthma

Y Morishima, S Ano, Y Ishii, S Ohtsuka… - Journal of …, 2013 - Wiley Online Library
… IL-17 is a proinflammatory cytokine mainly secreted from helper T (Th) 17 cells and is …
cytokines in steroid-insensitive asthma and discusses the prospects of novel therapeutic options …

MIF, MIF Alleles, and Prospects for Therapeutic Intervention in Autoimmunity

R Bucala - Journal of clinical immunology, 2013 - Springer
… application of MIF-directed therapies. The genetically defined variations in human MIF
expression also offer the prospect of a natural therapeutic window that may guide pharmacologic …

Phage therapy in prostatitis: Recent prospects

A Górski, E Jończyk-Matysiak… - Frontiers in …, 2018 - frontiersin.org
… its forms remain a serious therapeutic challenge. Inflammation … There are reports that phage
therapy is effective in chronic … therapy merits further research as an attractive therapeutic

The critical role of microRNAs in stress response: therapeutic prospect and limitation

J Du, M Li, Q Huang, W Liu, W Li, Y Li, Z Gong - Pharmacological Research, 2019 - Elsevier
… alterations in miRNAs that may promote a pro-inflammatory cytokine profile [67]. Some other
… it is expected to become a target for antioxidation therapy [65]. Overall, as discussed above, …

Prospects for CD40-directed experimental therapy of human cancer

AW Tong, MJ Stone - Cancer gene therapy, 2003 - nature.com
… heightened secretion of proinflammatory cytokines (IL-12, IL-6, TNFα) and chemokines (IL-8,
MIP-1α). Activation by CD154 in the presence of proinflammatory cytokines or IFNγ was …

… of Traditional Chinese Medicines on Preclinical in vivo Models of Brain Ischemia-Reperfusion-Injury: Prospects for Neuroprotective Drug Discovery and Therapy

T Peng, Y Jiang, M Farhan, P Lazarovici… - Frontiers in …, 2019 - frontiersin.org
… China’s clinical neurological therapeutic experience in the … brain IRI therapy in China with
significant therapeutic effects in … by targeting pro-inflammatory and anti-inflammatory cytokines, …

[HTML][HTML] Current status and future prospects of mesenchymal stem cell therapy for liver fibrosis

Y Guo, B Chen, L Chen, C Zhang… - Journal of Zhejiang …, 2016 - ncbi.nlm.nih.gov
… In general, MSC therapy for liver fibrosis is effective and … of MSC therapy for liver fibrosis
and the associated limitations, and we suggest some potential future applications of this therapy. …

[HTML][HTML] Drug-induced liver injury and prospect of cytokine based therapy; A focus on IL-2 based therapies

N Kumar, S Surani, G Udeani, S Mathew, S John… - Life Sciences, 2021 - Elsevier
… of DILI, cytokine-based therapies provide one of the relatively less explored avenues for
intervention. Hence, in this review we discussed the prospect of cytokine therapies for treating …

Immunotherapy strategies and prospects for acute lung injury: Focus on immune cells and cytokines

W Zhu, Y Zhang, Y Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
… that target the immune system is a meaningful therapeutic strategy, and the use of combination
cytokines concerned with the development of disease, this opens up new therapeutic

Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects

C Li, P Jiang, S Wei, X Xu, J Wang - Molecular cancer, 2020 - Springer
… for the rational design of checkpoint inhibitor-based combination therapies. Finally, we
propose possible treatment strategies that can be used to develop Treg-targeted therapies. …