Generation of a broadly useful model for COVID-19 pathogenesis, vaccination, and treatment

J Sun, Z Zhuang, J Zheng, K Li, RLY Wong, D Liu… - Cell, 2020 - cell.com
therapies (poly I:C and remdesivir). In summary, we describe a murine model of broad and
immediate utility to investigate COVID-19 pathogenesis and to evaluate new therapies and …

COVID-19 transmission, current treatment, and future therapeutic strategies

VS Salian, JA Wright, PT Vedell, S Nair… - Molecular …, 2021 - ACS Publications
therapeutic strategies to curb the virus, specifically focusing on the current efforts employed
for developing an effective vaccine and drug repurposing strategies … and pathogenesis of the …

Dysregulated interferon response and immune hyperactivation in severe COVID-19: targeting STATs as a novel therapeutic strategy

M Eskandarian Boroujeni, A Sekrecka… - Frontiers in …, 2022 - frontiersin.org
… In common with SARS-CoV and MERS-CoV infections, ARDS causes similar immunopathogenic
features and is the main cause of death in COVID-19 disease (4). Advanced age and …

SARS-CoV-2: Current trends in emerging variants, pathogenesis, immune responses, potential therapeutic, and vaccine development strategies

A Salimi-Jeda, S Abbassi, A Mousavizadeh… - International …, 2021 - Elsevier
… More than a year after the SARS-CoV-2 pandemic, the Coronavirus disease 19 (COVID-19) …
have been posed in controlling the COVID-19 infection. These problems include the various …

[HTML][HTML] COVID-19: Progress in diagnostics, therapy and vaccination

X Liu, C Liu, G Liu, W Luo, N Xia - Theranostics, 2020 - ncbi.nlm.nih.gov
… , might be a better therapeutic approach. Studies have indicated that … other studies investigating
combination therapy; these smaller … pathogenesis of SARS-CoV-2 deepens, combination …

Pharmacological mechanism of immunomodulatory agents for the treatment of severe cases of COVID-19 infection

Z Bahari, Z Jangravi, H Ghoshooni, MR Afarinesh… - Inflammation …, 2021 - Springer
pathogenesis of cytokine storm in COVID-19. In the following, we are going to review host
immune responses against COVID-19 … as a therapeutic strategy for severe cases of COVID-19

Pathogenesis and treatment of cytokine storm in COVID-19

M Soy, G Keser, MP Atagündüz - Turkish Journal of Biology, 2021 - journals.tubitak.gov.tr
… of nanomedicine including liposomes or synthetic nanoparticles to modulate macrophage
dysfunction and to inhibit dysregulated macrophages can be a novel therapeutic approach for …

SARS–CoV-2 immuno-pathogenesis and potential for diverse vaccines and therapies: opportunities and challenges

AR McGill, R Khalil, R Dutta, R Green, M Howell… - Infectious Disease …, 2021 - mdpi.com
… to successfully combat COVID-19, since no single therapy has … investigated against COVID-19
and will be reviewed herein. … ) was proposed as a therapeutic strategy by inhibiting viral …

nCOVID-19 pandemic: from molecular pathogenesis to potential investigational therapeutics

MT Kabir, MS Uddin, MF Hossain… - Frontiers in cell and …, 2020 - frontiersin.org
… virus, this widespread novel coronavirus disease 2019 (nCOVID-19) became a worldwide …
pollution may also affect the transmission pattern of COVID-19. Unfortunately, still, there is no …

[PDF][PDF] Immunopathological Properties of the Enigmatic COVID-19 and Therapeutic Interventions against It: an Update

S Roy - researchgate.net
COVID-19 and in the present review, we have summarized several potential therapeutic
strategies … is published daily throughout the world, the pathogenesis of COVID-19 still remains to …