Spondylarthropathies: from gut to target organs

EM Veys, H Mielants, M De Vos, C Cuvelier - Baillière's clinical …, 1996 - Elsevier
Recent studies strongly support the concept that gut and joint inflammation are closely
related. Progress also has been made in identifying individual mechanisms that contribute to …

Integrating the pathogenesis of spondyloarthritis: gut and joint united?

K De Wilde, K Debusschere, S Beeckman… - Current opinion in …, 2015 - journals.lww.com
A significant amount of data all point in the direction of arthritis and gut inflammation being
pathogenetically closely linked in the SpA concept. However, when it comes to therapeutic …

Immune linkages between inflammatory bowel disease and spondyloarthropathies

D Baeten, F De Keyser, H Mielants… - Current opinion in …, 2002 - journals.lww.com
Gut involvement is a prominent feature of spondyloarthropathy (SpA). Analysis of immune
alterations of the gut in SpA have shown two distinct aspects. On the one hand, gut …

Gut inflammation in the spondyloarthropathies

H Mielants, F De Keyser, D Baeten… - Current rheumatology …, 2005 - Springer
In this paper, the ample experimental, clinical, genetic, histopathologic, and immunologic
evidence for an important role of the gut in the pathogenesis of spondylarthropathy (SpA) …

The intimate relationship between gut and joint in spondyloarthropathies

P Jacques, H Mielants, K Coppieters… - Current opinion in …, 2007 - journals.lww.com
The intimate relationship between gut and joint in spondyloa... : Current Opinion in
Rheumatology The intimate relationship between gut and joint in spondyloarthropathies …

Bowel inflammation and the spondyloarthropathies

F De Keyser, D Elewaut, M De Vos, K De Vlam… - … Disease Clinics of North …, 1998 - Elsevier
The concept of spondyloarthropathies (SpA) gathers together a group of chronic diseases
with common clinical, biological, genetic and therapeutic characteristics. The concept forms …

Synovial and mucosal immunopathology in spondyloarthritis

B Vandooren, PP Tak, D Baeten - Molecular Mechanisms of …, 2009 - Springer
Chronic inflammation of musculoskeletal structures is the most prominent disease
manifestation of SpA. More specifically, the axial disease affects the spine, the sacroiliac …

Opportunities for immune modulation in the spondyloarthropathies with special reference to gut inflammation

F De Keyser, N Van Damme, M De Vos, H Mielants… - Inflammation …, 2000 - Springer
The spondyloarthropathies (SpA) are a related group of disorders, characterized primarily by
spondylitis, pauci-articular arthritis and enthesitis. The presence of subclinical gut …

The gut-joint axis in spondyloarthritis: immunological, microbial, and clinical insights

Z Qaiyum, M Lim, RD Inman - Seminars in Immunopathology, 2021 - Springer
The strong genetic and clinical overlaps between spondyloarthritis (SpA) and inflammatory
bowel disease (IBD) have placed much needed focus on the gut-joint axis of inflammation in …

Significance of intestinal inflammation in the pathogenesis of spondylarthropathies

H Mielants, EM Veys - Verhandelingen-Koninklijke Academie Voor …, 1996 - europepmc.org
The concept of spondylarthropathy (SpA) gathers together a group of chronic diseases with
common clinical, biological, genetic and therapeutic characteristics. The concept forms a …