Most of the bone and kidney-related functions of parathyroid hormone (PTH) and
parathyroid hormone-related peptide (PTHrP) are thought to be mediated by the PTH/PTHrP …

Parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHrP) bind to a
common PTH/PTHrP receptor. To explore structure-function relations in these ligands, we …

PTH and PTH-related peptide (PTHrP) bind to the PTH/PTHrP receptor and stimulate cAMP
accumulation with similar efficacy. Only PTH activates the PTH2 receptor. To examine the …

Carboxyl-terminal fragments of PTH (C-PTH) appear to have biological properties different
from those mediated by the amino-terminal portions of PTH and PTH-related peptide …

The carboxyl-terminal portions of parathyroid hormone (PTH)-(1–34) and PTH-related
peptide (PTHrP)-(1–36) are critical for high affinity binding to the PTH/PTHrP receptor (P1R) …

The recombinant human PTH/PTH-related peptide (PTHrP) receptor, when transiently
expressed in COS-7 cells, binds [Nle8, 18, Tyr34] bovine PTH-(7-34) amide [PTH-(7-34)] …

PTH and PTHrP use the same G protein-coupled receptor, the PTH/PTHrP receptor (PTHR),
to mediate their distinct biological actions. The extent to which the mechanisms by which the …

Identical complementary DNAs (cDNAs) that encode a 593-amino acid human PTH
(PTH)/PTH-related peptide (PTHrP) receptor were isolated by hybridization techniques from …

The type 1 receptor (PTH1R) for parathyroid hormone (PTH) and parathyroid hormone-
related peptide (PTHrP) is a G protein-coupled receptor that is highly expressed in bone and …

While abundant information is available characterizing PTH receptor properties in other
species, data on human PTH receptors is very limited. We have been interested in the …