The purpose of this study was to evaluate the effect of amezinium metilsulfate (amezinium)
on orthostatic hypotension (OH) and physical fitness in cervical cord injuries. Eighteen …

BACKGROUND: Dialysis-induced hypotension is a very common but difficult complication to
manage. Amezinium methylsulfate is a newly developed sympatho-mimetic agent which has …

Spinal cord injury is a devastating chronic condition resulting in temporary or permanent
motor, sensory or autonomic dysfunction of the cord. The manifestation of spinal cord injury …

Objectives To determine the effect of an escalating dose of droxidopa (100, 200, and
400mg) compared with placebo on seated blood pressure (BP) in hypotensive individuals …

Amezinium metilsulfate is a new, indirectly acting sympathomimetic drug which exclusively
affects postganglionic sympathetic neurons and inhibits both intraneuronal monoamine …

Orthostatic hypotension (OH) is one of the complications in patients with spinal cord injury
(SCI) particularly in the acute stage. Impairment in the autonomic nervous system, usually in …

20 min after single iv administration of 10 mg 4-amino-6-methoxy-1-phenyl-pyridazinium
methyl sulfate (ameziniummetilsulfate, LU 1631, Regulton), in the following briefly called …

Mukand J, Karlin L, Barrs K, Lublin P. Midodrine for the management of orthostatic
hypotension in patients with spinal cord injury: a case report. Arch Phys Med Rehabil 2001; …

The antihypotensive effect of amezinium metilsulfate, a newly developed antihypotensive
agent, and the drug's effect on norepinephrine, epinephrine, and atrial natriuretic peptide …

Abstract Treatment of orthostatic hypotension is an important consideration for many patients
with spinal cord injuries, especially those with an injury to the cervical cord. Delay in …