The effects of unfractionated heparin on survival in patients with malignancy–a systematic review

SM Smorenburg, RJK Hettiarachchi… - Thrombosis and …, 1999 - thieme-connect.com
Clinical and experimental studies have suggested that unfractionated heparin (UFH) effects
malignancy progression. We reviewed all published clinical reports concerning the effects of …

[HTML][HTML] The effect of low‐molecular‐weight heparin on cancer survival. A systematic review and meta‐analysis of randomized trials

A Lazo‐Langner, GD Goss, JN Spaans… - Journal of Thrombosis …, 2007 - Elsevier
Background: Low‐molecular‐weight heparins (LMWH) have an antitumor effect in vitro and
in experimental animal models of malignancy. Retrospective data suggest that it might …

[HTML][HTML] The effect of low molecular weight heparin on survival in cancer patients: an updated systematic review and meta‐analysis of randomized trials

D Sanford, A Naidu, N Alizadeh… - Journal of Thrombosis and …, 2014 - Elsevier
Background Tumors may exploit the coagulation system to enhance the survival and
dissemination of cancer cells. Some studies have suggested that heparin and low molecular …

Improved cancer mortality with low-molecular-weight heparin treatment: a review of the evidence

RH Cosgrove, LR Zacharski, E Racine… - … in thrombosis and …, 2002 - thieme-connect.com
Work with low-molecular-weight heparins (LMWHs) continues to provide suggestions for
survival advantages among patients with cancer diagnoses. Momentum is building in …

The efficacy and safety of low molecular weight heparin administration to improve survival of cancer patients: a systematic review and meta-analysis

J Montroy, MM Lalu, RC Auer, E Grigor… - Thrombosis and …, 2020 - thieme-connect.com
Background Low molecular weight heparins (LMWH) are often used as a first-line therapy
for the prevention of thrombosis in cancer patients. Preclinical evidence from animal models …

Low-molecular-weight heparin and cancer survival: review of the literature and pooled analysis of 1,726 patients treated for at least three months

S Conti, F Guercini, A Iorio - Pathophysiology of Haemostasis and …, 2003 - karger.com
Background: Heparin has been the main subject of intensive investigation and clinical use
because of its therapeutic anticoagulant properties. It also exhibits many other biological …

Low-molecular-weight heparin in patients with advanced cancer: a phase 3 clinical trial

K Sideras, PL Schaefer, SH Okuno, JA Sloan… - Mayo Clinic …, 2006 - Elsevier
OBJECTIVE To prospectively assess whether low-molecular-weight heparin (LMWH)
provides a survival benefit in patients with advanced cancer. PATIENTS AND METHODS …

The efficacy and safety of low-molecular-weight heparin use for cancer treatment: a meta-analysis

DH Che, JY Cao, LH Shang, YC Man, Y Yu - European journal of internal …, 2013 - Elsevier
BACKGROUND: Low-molecular-weight heparin (LMWH) has an anti-tumour effect in-vitro
and in animal models of malignancy; however, the evidence from clinical trials is …

Heparin and cancer

LR Zacharski, DL Ornstein - Thrombosis and haemostasis, 1998 - thieme-connect.com
Heparin has been the subject of intensive investigation for decades by both basic and
clinical scientists because of its usefulness as a therapeutic anticoagulant (1). In addition to …

Do heparins do more than just treat thrombosis? The influence of heparins on cancer spread

RJK Hettiarachchi, SM Smorenburg… - Thrombosis and …, 1999 - thieme-connect.com
The influence of unfractionated heparin (UFH) and other anticoagulants on the spread of
cancer has been reported since the early 1960s. 1 However, clinical studies investigating …