We have examined the relationship between transcription and chromatin structure using a
tandem array of the mouse mammary tumor virus (MMTV) promoter driving a ras reporter …

The role of histone acetylation as a key mechanism of transcriptional regulation has been
well established. Recent advances suggest that histone acetyltransferases also play …

The ATM-related TRRAP protein is a component of several different histone
acetyltransferase (HAT) complexes but lacks the kinase activity characteristic of other ATM …

The p300/cAMP response element-binding protein-binding protein (CBP) family members
include human p300 and cAMP response element-binding protein-binding protein, which …

The monocytic leukemia zinc finger protein (MOZ) gene is rearranged in t (8; 16)(p11; p13), t
(8; 22)(p11; q13) and inv (8)(p11q13) associated with acute myeloid leukemia. The other …

The acetylation state of histones plays a central role in determining gene expression in
chromatin. The reestablishment of the acetylation state of nucleosomes after DNA replication …

Introduction 2.1. Histone acetyltransferase and deacetylase complexes 2.2. SWI/SNF family
of chromatin remodeling complexes 3. Activator targeting of histone acetyltransferase …

It is well established that acetylation of histone and nonhistone proteins is intimately linked
to transcriptional activation. However, loss of acetyltransferase activity has also been shown …

Regulation of HIV‐1 gene expression by the viral Tat trans‐activator is a critical step in the
viral life cycle. Tat acts as a highly unusual transcription factor that interacts with a stem‐loop …

Specific changes in chromatin structure are associated with transcriptional regulation. These
chromatin alterations include both covalent modifications of the amino termini of histones as …