During nucleosome assembly in vivo, newly synthesized histone H4 is specifically
diacetylated on lysines 5 and 12 within the H4 NH 2-terminal tail domain. The highly …

One of the key questions in the current molecular genetics of eukaryotes is how genetic
information is retrieved from tightly packed chromatin. Acetylation of core histone N-termini is …

[Frontiers in Bioscience, d954-959, August 1, 2001] 954 IMPORTANCE OF THE REGULATION
OF NUCLEAR RECEPTOR DEGRADATION Andrew P. D Page 1 [Frontiers in Bioscience …

Interferon regulatory factor-2 (IRF-2) is a transcription factor of the IRF family that represses
interferon-mediated gene expression. In the present study, we show that human monocytic …

Infected-cell protein 0 encoded by bovine herpesvirus 1 (BHV-1)(bICP0) is necessary for
efficient productive infection, in large part, because it activates all 3 classes of BHV-1 genes …

Many of the functions ascribed to p53 tumor suppressor protein are mediated through
transcription regulation. We have shown that p53 represses hepatic-specific α-fetoprotein …

Nucleosomes assembled by wrapping the DNA around a histone octamer are the basic
building blocks of chromatin [1]. This array of nucleosomes along the DNA is further …

Using a yeast two‐hybrid assay we detected an interaction between the N‐terminal region of
histone H4 (amino acids 1–59) and a fragment of the bromodomain factor 1 protein …

The basic element of chromatin is the nucleosome. Histones H4, H3, H2A and H2B form the
core histone octamer by protein-protein interactions of their folded domains. The free …

TAF II s are conserved components of the TFIID, TFTC and SAGA‐related mRNA
transcription complexes. In yeast (y), yTAF II 17 is required broadly for transcription, but …