[HTML][HTML] CREB-binding protein and p300 in transcriptional regulation

N Vo, RH Goodman - Journal of Biological Chemistry, 2001 - ASBMB
CREB1-binding protein (CBP) and p300 are believed to participate in the activities of
hundreds of different transcription factors (see Fig. 1). Current models suggest that the …

[HTML][HTML] CREB-binding protein activates transcription through multiple domains

DL Swope, CL Mueller, JC Chrivia - Journal of Biological Chemistry, 1996 - ASBMB
CREB-binding protein (CBP) functions as a coactivator molecule for a number of
transcription factors including CREB, c-Fos, c-Jun, c-Myb, and several nuclear receptors …

CBP/p300 in cell growth, transformation, and development

RH Goodman, S Smolik - Genes & development, 2000 - genesdev.cshlp.org
CREB binding protein (CBP) and p300 were both identified initially in protein interaction
assays–the former through its association with the transcription factor CREB (Chrivia et al …

Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition

F Wang, CB Marshall, M Ikura - Cellular and Molecular Life Sciences, 2013 - Springer
In eukaryotic cells, gene transcription is regulated by sequence-specific DNA-binding
transcription factors that recognize promoter and enhancer elements near the transcriptional …

[HTML][HTML] Phosphorylation of p300 at serine 89 by protein kinase C

LW Yuan, JE Gambee - Journal of Biological Chemistry, 2000 - ASBMB
CREB-binding protein (CBP)/p300 plays an important role in the connection of many
different signal transduction pathways and the promotion of certain differentiation and …

CBP and p300: HATs for different occasions

E Kalkhoven - Biochemical pharmacology, 2004 - Elsevier
The transcriptional coactivators CREB binding protein (CBP) and p300 are key regulators of
RNA polymerase II-mediated transcription. Genetic alterations in the genes encoding these …

Factor-specific modulation of CREB-binding protein acetyltransferase activity

V Perissi, JS Dasen, R Kurokawa… - Proceedings of the …, 1999 - National Acad Sciences
CREB-binding proteins (CBP) and p300 are essential transcriptional coactivators for a large
number of regulated DNA-binding transcription factors, including CREB, nuclear receptors …

Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation

JR Cardinaux, JC Notis, Q Zhang, N Vo… - … and cellular biology, 2000 - Taylor & Francis
Phosphorylation of the transcription factor CREB leads to the recruitment of the coactivator,
CREB binding protein (CBP). Recent studies have suggested that CBP recruitment is not …

[HTML][HTML] Transcriptional control: versatile molecular glue

R Janknecht, T Hunter - Current Biology, 1996 - cell.com
Transcriptional control: Versatile molecular glue: Current Biology Skip to Main Content
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[HTML][HTML] Acetylation of cAMP-responsive element-binding protein (CREB) by CREB-binding protein enhances CREB-dependent transcription

Q Lu, AE Hutchins, CM Doyle, JR Lundblad… - Journal of Biological …, 2003 - ASBMB
The coactivator function of cAMP-responsive element-binding protein (CREB)-binding
protein (CBP) is partly caused by its histone acetyltransferase activity. However, it has …