Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
Y Zhang, D Reinberg - Genes & development, 2001 - genesdev.cshlp.org
In this review, we discuss recent advances made on histone methylation and its diverse
functions in regulating gene expression. Methylation of histone polypeptides might be static …
functions in regulating gene expression. Methylation of histone polypeptides might be static …
Histone methylation versus histone acetylation: new insights into epigenetic regulation
JC Rice, CD Allis - Current opinion in cell biology, 2001 - Elsevier
Post-translational addition of methyl groups to the amino-terminal tails of histone proteins
was discovered more than three decades ago. Only now, however, is the biological …
was discovered more than three decades ago. Only now, however, is the biological …
Histone acetylation and methylation: combinatorial players for transcriptional regulation
W An - Chromatin and Disease, 2007 - Springer
Post-synthetic modification of histone proteins in chromatin architecture plays a central role
in the epigenetic regulation of transcription. Histone acetylation and methylation are the two …
in the epigenetic regulation of transcription. Histone acetylation and methylation are the two …
The emerging functions of histone demethylases
Epigenetic information refers to heritable changes in gene function that are stable between
cell divisions but which is not a result of changes in the DNA sequence. Part of the …
cell divisions but which is not a result of changes in the DNA sequence. Part of the …
Molecular mechanisms and potential functions of histone demethylases
SM Kooistra, K Helin - Nature reviews Molecular cell biology, 2012 - nature.com
Histone modifications are thought to regulate chromatin structure, transcription and other
nuclear processes. Histone methylation was originally believed to be an irreversible …
nuclear processes. Histone methylation was originally believed to be an irreversible …
Regulation of histone methylation by demethylimination and demethylation
Histone methylation has important roles in regulating transcription, genome integrity and
epigenetic inheritance. Historically, methylated histone arginine and lysine residues have …
epigenetic inheritance. Historically, methylated histone arginine and lysine residues have …
Histone lysine methylation: a signature for chromatin function
RJ Sims, K Nishioka, D Reinberg - TRENDS in Genetics, 2003 - cell.com
The rapid progress in deciphering the processes of covalent histone modifications has
broadened our understanding of transcriptional regulation. Histone lysine methylation, along …
broadened our understanding of transcriptional regulation. Histone lysine methylation, along …
Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases
N Mosammaparast, Y Shi - Annual review of biochemistry, 2010 - annualreviews.org
The importance of histone methylation in gene regulation was suggested over 40 years ago.
Yet, the dynamic nature of this histone modification was recognized only recently, with the …
Yet, the dynamic nature of this histone modification was recognized only recently, with the …
Structure and function of histone methyltransferases
RC Trievel - Critical Reviews™ in Eukaryotic Gene Expression, 2004 - dl.begellhouse.com
Histones are the major protein constituent of chromatin in the eukaryotic nucleus. These
proteins undergo a host of different post-translational modifications, including …
proteins undergo a host of different post-translational modifications, including …
An epigenetic road map for histone lysine methylation
M Lachner, RJ O'Sullivan… - Journal of cell …, 2003 - journals.biologists.com
Histone N-termini (tails) undergo diverse post-translational modifications, including
acetylation, phosphorylation, methylation, ubiquitination and ADP-ribosylation (van Holde …
acetylation, phosphorylation, methylation, ubiquitination and ADP-ribosylation (van Holde …