This overview of the coagulation biology of cancer is intended primarily for those unfamiliar
with the link between the coagulation mechanism and neoplasia. Because the literature on …

Critical information on the nature of the coagulation-cancer interaction has been obtained
from a number of sources. In vitro/ex vivo sources of information include assays performed …

The purpose of this review is to demonstrate the potential for development of coagulation-
reactive drugs for experimental cancer treatment. Improved cancer outcome has been …

Development of cancer is associated with activation of blood coagulation. The results of
laboratory tests clearly demonstrate that fibrin formation and dissolution is continuously …

The relationship between increased clotting and malignancy is well recognized, though the
bidirectional development of this association is often overlooked. In the challenging cancer …

A hypercoagulable or prothrombotic state of malignancy occurs due to the ability of tumor
cells to activate the coagulation system. It has been estimated that hypercoagulation …

Pathogenesis of the prothrombotic state of cancer patients is due, at least in part, to the
ability of cancer cells to activate the coagulation system. Several complex and not fully …

Malignancy affects the hemostatic system and the hemostatic system affects malignancy. In
cancer patients there are a number of coagulation abnormalities which provide the …

There is an intimate relationship between the processes involved in malignancy and
hemostasis. The mechanisms by which malignancy promotes thrombosis are reviewed …

Rapid progress has been made recently in our understanding of the pathogenesis of
coagulation activation in malignancy and mechanisms by which the coagulation mechanism …