[PDF][PDF] The Aspartate 69 Residue of the Calcitonin-Like Receptor is Required for its Functional Expression together with Receptor-Activity-Modifying Proteins 1 and–2

LM Ittner, F Luessi, D Koller… - Short N-Terminal …, 2004 - research-collection.ethz.ch
The calcitonin-like receptor (CLR) associated with receptor-activitymodifying proteins
(RAMP)-1 or-2 recognizes calcitonin gene-related peptide (CGRP) and adrenomedullin …

Aspartate69 of the calcitonin-like receptor is required for its functional expression together with receptor-activity-modifying proteins 1 and-2

LM Ittner, F Luessi, D Koller, W Born, JA Fischer… - Biochemical and …, 2004 - Elsevier
The calcitonin-like receptor (CLR) associated with receptor-activity-modifying proteins
(RAMP) 1 or-2 recognizes calcitonin gene-related peptide (CGRP) and adrenomedullin …

Three receptor-activity-modifying proteins define calcitonin gene-related peptide or adrenomedullin selectivity of the mouse calcitonin-like receptor in COS-7 cells

K Husmann, W Born, JA Fischer, R Muff - Biochemical pharmacology, 2003 - Elsevier
Receptors for calcitonin gene-related peptide (CGRP) and adrenomedullin (AM) are
heterodimeric complexes of the calcitonin-like receptor (CLR) together with associated …

Identification of the human receptor activity-modifying protein 1 domains responsible for agonist binding specificity

K Kuwasako, K Kitamura, Y Nagoshi, YN Cao… - Journal of Biological …, 2003 - ASBMB
When co-expressed with receptor activity-modifying protein (RAMP) 1, calcitonin receptor-
like receptor (CRLR) can function as a receptor for both calcitonin gene-related peptide …

[PDF][PDF] Short N-terminal regions of the calcitonin-like receptor define ligand specificity

D Koller - 2004 - research-collection.ethz.ch
Summary Calcitonin (CT), α-and β-CT gene-related peptide (CGRP), adrenomedullin (AM),
and amylin belong to the calcitonin family of peptides. Six or seven amino acid ring …

Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptor

CM Koth, N Abdul-Manan, CA Lepre, PJ Connolly… - Biochemistry, 2010 - ACS Publications
The calcitonin gene-related peptide (CGRP) receptor is a heterodimer of two membrane
proteins: calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein 1 …

Identification of specific calcitonin-like receptor residues important for calcitonin gene-related peptide high affinity binding

S Banerjee, J Evanson, E Harris, SL Lowe… - BMC …, 2006 - Springer
Background Calcitonin gene-related peptide (CGRP) is a vasoactive neuropeptide whose
biological activity has potential therapeutic value for many vascular related diseases. CGRP …

[HTML][HTML] The extreme N-terminus of the calcitonin-like receptor contributes to the selective interaction with adrenomedullin or calcitonin gene-related peptide

D Koller, W Born, K Leuthäuser, B Flühmann… - FEBS letters, 2002 - Elsevier
The calcitonin (CT)-like (CL) receptor is a CT gene-related peptide (CGRP) receptor or an
adrenomedullin (AM) receptor when co-expressed with receptor-activity-modifying proteins …

Receptor activity‐modifying protein‐dependent effects of mutations in the calcitonin receptor‐like receptor: implications for adrenomedullin and calcitonin gene …

HA Watkins, CS Walker, KN Ly… - British journal of …, 2014 - Wiley Online Library
Background and Purpose Receptor activity‐modifying proteins (RAMP s) define the
pharmacology of the calcitonin receptor‐like receptor (CLR). The interactions of the different …

Identification and pharmacological characterization of domains involved in binding of CGRP receptor antagonists to the calcitonin-like receptor

CA Salvatore, JJ Mallee, IM Bell, CB Zartman… - Biochemistry, 2006 - ACS Publications
The calcitonin-like receptor (CLR) and the calcitonin receptor (CTR) interact with receptor
activity-modifying protein 1 (RAMP1) at the cell surface to form heterodimeric receptor …