In the present study expression levels of secretin and secretin receptor mRNAs in several
brain regions of rats ranging in age from postnatal days 7 to 60 were investigated by …

Secretin shows a wide distribution in the brain. Functional significance of central secretin is
stressed since it has been associated with autism and schizophrenia. The presence of the …

The expression and spatial distribution of secretin and its receptor in human cerebellum
were investigated by in situ hybridization and immunohistochemical techniques. Secretin …

Secretin is a classical gastrointestinal peptide while its neuroactive functions in the central
nervous system have recently been consolidated. In the past, there was little information …

Although the existence of the receptor for secretin in the brain was suggested, the
localization of secretin receptor and the neuronal function of secretin have not been clarified …

Existence of the gastro‐intestinal peptide secretin in the CNS has been a matter of debate,
and contrasting results have been reported, altogether indicating that the CNS is not a major …

Secretin is a gut peptide hormone that is also expressed in the CNS. To explore the potential
neuroactive role of secretin in the brain, we have generated secretin deficient mice. Secretin …

The binding of [125I] secretin to rat brain membranes was investigated. Radiolabeled
secretin bound with high affinity (KD= 0.2 nM) to a single class of noninteracting sites …

Secretin immunoreactivity was detected in the central nervous system of the rat and pig with
a highly specific radioimmunoassay. The secretin immunoreactivity in the rat and pig brain …

Secretin is a neuropeptide that is expressed in distinct central neurones. As there is no
information on how the secretin gene is regulated in neuronal cells, a well established …