Secretin is a classical gastrointestinal hormone and only until recently have its neuroactive
roles are being substantiated. In this study, the precise localizations of the transcripts and …

Secretin was first discovered as a gastrointestinal hormone a century ago, and to date, the
role of secretin in regulating functions of exocrine pancreas is firmly established. The notion …

Secretin, a 27-amino-acid brain-gut hormone, is a putative neuropeptide believed to have
neuromodulatory effects in the central nervous system (CNS). Secretin and its receptor are …

The functional role of secretin outside the gastrointestinal system has been a mystery to
endocrinologists for many years. With the availability of secretin‐and secretin receptor …

The discovery of secretin initiated the field of endocrinology. Over the past century, multiple
gastrointestinal functions of secretin have been extensively studied, and it was discovered …

Secretin is a polypeptide hormone initially identified for its gastrointestinal functions.
However, emerging evidences show wide distribution of secretin and secretin receptor …

Since its initial discovery, secretin is now coined as a classical hormone with widespread
distribution. In particular, numerous studies have demonstrated the abundant expression of …

Previous studies demonstrated that secretin could be released from the cerebellum, where it
exerts a facilitatory action on the GABAergic inputs into the Purkinje neurons. In the present …

Secretin, a 27-amino acid gastrointestinal peptide, was initially discovered based on its
activities in stimulating pancreatic juice. In the past 20 years, secretin was demonstrated to …

Secretin holds a unique place in the history of endocrinology and gastrointestinal
physiology, as it is the first peptide designated as a hormone. During the last century since …