Peroxisome proliferator-activated receptor-γ (PPARγ) plays a role in adipocyte differentiation
and insulin sensitization. We identified and characterized a new C/T substitution at position …

Most, if not all, of physiological and behavioral processes exhibit circadian rhythms.
Recently, molecular clocks similar to those operating in the suprachiasmatic nucleus (SCN) …

Peroxisome proliferator-activated receptor γ (PPARγ) interacts with retinoid X receptor
(RXR) on PPAR response elements (PPREs) to regulate transcription of PPAR-responsive …

Brown adipose tissue (BAT) is a specialized mammalian tissue and a site of adaptive
thermogenesis. Although the metabolic functions of brown and white adipocytes are distinct …

Nuclear receptors are a family of ligand dependent transcription factors which have
important roles in control of growth and differentiation in many cell types. This review will …

The identification of gene mutations that cause lipodystrophies, conditions characterized by
a lack of normal adipose tissue, has revealed new proteins that play a role in adipocyte …

Steatosis is one of the most common liver diseases and is associated with the metabolic
syndrome. A line of evidence suggests that peroxisome proliferator–activated receptor …

Psoriasis is a chronic inflammatory condition affecting 1–3% of the world's population.
Despite the availability of several agents, therapeutic options remain limited. With a better …

The peroxisome proliferator-activated receptors (PPARs) comprise a group of related
transcription factors that serve to regulate a number of cellular processes that are central to …

1 The Nuclear Receptor Corepressors NCoR and SMRT Decrease PPARγ Transcriptional
Activity and Repress 3T3-L1 Adipogenesis Chri Page 1 1 The Nuclear Receptor Corepressors …