Although Bizzozero identified platelets as a blood component critical for hemostasis in 1882
(1), the central role of platelets in atherogenesis is just now being recognized (2). During …

Platelets are key players in arterial thrombosis and have become important targets in the
primary and secondary prevention of atherothrombosis. Antiplatelet drugs are primarily …

A common pathophysiological course in vascular diseases is an overwhelming activation
and aggregation of blood platelets, which results in atherothrombosis. By causing the last …

Antiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and
over the last few years spectacular advancements in this field have been recorded. This is …

Coronary thrombosis is a fundamental event in the pathophysiology of atherosclerotic coron-
ary artery disease, being involved in both the development of atheroma and its lethal …

The role of blood components including platelets, in initiating inflammation, endothelial
dysfunction, atherosclerosis, thrombus formation, thrombus growth, and acute vascular …

Over the past decade, the platelet has emerged as a pivotal entity in cardiovascular
diseases. Indeed, the'preeminence of the platelet'has spawned a variety of drugs that have …

The excessive accumulation of platelets at sites of vascular injury is a key event in the
development of arterial thrombosis, the principal pathogenic mechanism underlying the …

Antiplatelet therapy has an essential role in the treatment of cardiovascular disease. In this
article, we discuss the characteristics of current, new and emerging antiplatelet drugs, their …

Platelets are now regarded as playing a dominant role in cardiovascular medicine since our
recent understanding of acute coronary syndrome as an atherothrombotic process. This …