Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor regulating an
array of diverse functions in a variety of cell types including regulation of genes associated …

The differentiation of preadipocytes into adipocytes requires the suppression of canonical
Wnt signaling, which appears to involve a peroxisome proliferator-activated receptor γ …

The Wnt/β-catenin signalling pathway appears to operate to maintain the undifferentiated
state of preadipocytes by inhibiting adipogenic gene expression. To define the mechanisms …

The peroxisome proliferator-activated receptor-γ (PPARγ) transcription factor plays a pivotal
role in adipocyte differentiation and metabolic regulation. The transcriptional activity of …

Adipocyte differentiation is driven by the expression and activation of three transcription
factor families: the differentially expressed CAAT/enhancer binding proteins (C/EBPs) α, β …

Adipocyte differentiation is regulated both positively and negatively by external growth
factors such as insulin, platelet-derived growth factor (PDGF), and epidermal growth factor …

Peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein
α (C/EBPα) are key activators of adipogenesis. They mutually induce the expression of each …

Stimulation of adipogenesis in mouse preadipocytes requires C/EBPβ as well as activation
of the MEK/extracellular signal-regulated kinase (ERK) signaling pathway. In this study, we …

Adipocyte differentiation is controlled by a tightly regulated transcriptional cascade in which
PPARγ and members of the C/EBP family are key players. Here we review the roles of …

PPARγ and C/EBPα are critical transcription factors in adipogenesis, but the precise role of
these proteins has been difficult to ascertain because they positively regulate each other's …