Base excision repair (BER) averts the cytotoxic and mutagenic effects of most endogenously
produced DNA damage, including lesions that arise spontaneously due to the intrinsic …

Base excision repair (BER) proteins act upon a significantly broad spectrum of DNA lesions
that result from endogenous and exogenous sources. Multiple sub-pathways of BER (short …

Base excision repair (BER) is a major DNA repair pathway employed in mammalian cells
that is required to maintain genome stability, thus preventing several human diseases, such …

Base excision repair (BER) is an essential DNA repair pathway involved in the maintenance
of genome stability and thus in the prevention of human diseases, such as premature aging …

DNA base damage and non-coding apurinic/apyrimidinic (AP) sites are ubiquitous types of
damage that must be efficiently repaired to prevent mutations. These damages can occur in …

Covalent alterations of DNA bases, which may have promutagenic or cytotoxic effects, are
major consequences of endogenous DNA damage caused by hydrolysis, reactive oxygen …

Base excision repair (BER) is a frontline repair system that is responsible for maintaining
genome integrity and thus preventing premature aging, cancer and many other human …

Reactive oxygen species continuously assault the structure of DNA resulting in oxidation
and fragmentation of the nucleobases. Both oxidative DNA damage itself and its repair …

Base excision repair (BER) is the major pathway responsible for averting the mutagenic and
cytotoxic effects of spontaneous hydrolytic, oxidative, and non-enzymatic alkylation DNA …

Base excision repair (BER) corrects forms of oxidative, deamination, alkylation, and abasic
single-base damage that appear to have minimal effects on the helix. Since its discovery in …