[图书][B] The saccharomyces cerevisiae arginine attenuator peptide regulates translation and mRNA decay

A Gaba - 2005 - search.proquest.com
Abstract The Saccharomyces cerevisiae CPA1 mRNA 5′-leader contains an evolutionarily
conserved 25-codon upstream open reading frame (uORF), which genetic studies had …

Ribosome occupancy of the yeast CPA1 upstream open reading frame termination codon modulates nonsense-mediated mRNA decay

A Gaba, A Jacobson, MS Sachs - Molecular cell, 2005 - cell.com
Saccharomyces cerevisiae CPA1 mRNA contains an upstream open reading frame (uORF)
encoding the arginine attenuator peptide (AAP). Negative translational regulation of CPA1 …

[图书][B] Analyses of the fungal arginine attenuator peptide's role in the regulation of ribosome stalling

P Fang - 2003 - search.proquest.com
The arginine attenuator peptides (AAP), specified by an evolutionarily conserved upstream
open reading frame (uORF) in mRNAs specifying small subunit of carbamoyl phosphate …

A highly conserved mechanism of regulated ribosome stalling mediated by fungal arginine attenuator peptides that appears independent of the charging status of …

Z Wang, A Gaba, MS Sachs - Journal of Biological Chemistry, 1999 - ASBMB
The Arg attenuator peptide (AAP) is an evolutionarily conserved peptide involved in Arg-
specific negative translational control. It is encoded as an upstream open reading frame …

[图书][B] The evolutionarily conserved arginine attenuator peptide regulates the movement of ribosomes that have translated it

Z Wang - 2000 - search.proquest.com
The major focus of this study is to elucidate the mechanism of translational control of arg-2.
arg-2 is a gene involved in Neurospora crassa arginine (Arg) biosynthesis, and translation of …

The evolutionarily conserved eukaryotic arginine attenuator peptide regulates the movement of ribosomes that have translated it

Z Wang, P Fang, MS Sachs - Molecular and cellular biology, 1998 - Taylor & Francis
Translation of the upstream open reading frame (uORF) in the 5′ leader segment of the
Neurospora crassa arg-2 mRNA causes reduced initiation at a downstream start codon …

The arginine attenuator peptide interferes with the ribosome peptidyl transferase center

J Wei, C Wu, MS Sachs - Molecular and cellular biology, 2012 - Taylor & Francis
The fungal arginine attenuator peptide (AAP) is encoded by a regulatory upstream open
reading frame (uORF). The AAP acts as a nascent peptide within the ribosome tunnel to stall …

Sequence requirements for ribosome stalling by the arginine attenuator peptide

CC Spevak, IP Ivanov, MS Sachs - Journal of Biological Chemistry, 2010 - ASBMB
The 5′ regions of eukaryotic mRNAs often contain upstream open reading frames (uORFs).
The Neurospora crassa arg-2 uORF encodes the 24-residue arginine attenuator peptide …

[PDF][PDF] Specific requirements for translational regulation by a nascent peptide that stalls ribosomes in response to arginine

CC Spevak - 2006 - digitalcollections.ohsu.edu
Nascent polypeptides can control translation. Signal peptides that direct polypeptides to the
ER associate with the signal recognition particle to halt translation elongation until the …

A nascent polypeptide domain that can regulate translation elongation

P Fang, CC Spevak, C Wu… - Proceedings of the …, 2004 - National Acad Sciences
The evolutionarily conserved fungal arginine attenuator peptide (AAP), as a nascent
peptide, stalls the translating ribosome in response to the presence of a high concentration …