Adipogenesis: cellular and molecular aspects

B Fève - Best Practice & Research Clinical Endocrinology & …, 2005 - Elsevier
Obesity and lipoatrophy are major risks for insulin resistance, non-insulin-dependent
diabetes and cardiovascular disease. In the past three decades, significant advances have …

Adipocyte differentiation: from fibroblast to endocrine cell

FM Gregoire - Experimental Biology and Medicine, 2001 - journals.sagepub.com
Recent advances regarding the biology of adipose tissue have demonstrated that white
adipose tissue (WAT) plays a central role in the regulation of energy balance and acts as a …

Transcriptional control of adipocyte formation

SR Farmer - Cell metabolism, 2006 - cell.com
A detailed understanding of the processes governing adipose tissue formation will be
instrumental in combating the obesity epidemic. Much progress has been made in the last …

Adipogenesis and metabolic health

AL Ghaben, PE Scherer - Nature reviews Molecular cell biology, 2019 - nature.com
Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

Adipogenesis

K Sarjeant, JM Stephens - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body
insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue …

The fat controller: adipocyte development

JM Stephens - PLoS biology, 2012 - journals.plos.org
Obesity is a condition characterized by excess adipose tissue that results from positive
energy balance and is the most common metabolic disorder in the industrialized world. The …

Adipocyte differentiation from the inside out

ED Rosen, OA MacDougald - Nature reviews Molecular cell biology, 2006 - nature.com
Improved knowledge of all aspects of adipose biology will be required to counter the
burgeoning epidemic of obesity. Interest in adipogenesis has increased markedly over the …

Transcriptional factors that promote formation of white adipose tissue

UA White, JM Stephens - Molecular and cellular endocrinology, 2010 - Elsevier
Adipocytes are highly specialized cells that play a major role in energy homeostasis in
vertebrate organisms. Excess adipocyte size or number is a hallmark of obesity, which is …

Adipocyte differentiation

JM Moreno-Navarrete, JM Fernández-Real - Adipose tissue biology, 2017 - Springer
Adipocyte differentiation is a highly controlled process that has been extensively studied for
the last 25 years. Two different kinds of in vitro experimental models, essential in …

Adipogenesis: a complex interplay of multiple molecular determinants and pathways

MA Ambele, P Dhanraj, R Giles, MS Pepper - International journal of …, 2020 - mdpi.com
The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …