[图书][B] Complex regulation of Myc/Max functions by histone acetyltransferases and deacetylases
F Faiola - 2006 - search.proquest.com
The Myc oncoprotein is a DNA sequence-specific transcription factor that regulates
transcription of a wide variety of genes involved in the control of cell growth, proliferation …
transcription of a wide variety of genes involved in the control of cell growth, proliferation …
El envejecimiento de los organismos: modelos
LA García, DC Santiago - Biogerontología Serie Textos …, 2006 - books.google.com
En este capítulo abordamos el envejecimiento desde el punto de vista de algunos de los
modelos empleados para su estudio, que abarcan en orden creciente de complejidad …
modelos empleados para su estudio, que abarcan en orden creciente de complejidad …
[PDF][PDF] Posttranslational modifications of Forkhead box O transcription factors
AA van der Horst - researchgate.net
IGF insulin-like growth factor Ig HC immunoglobulin heavy chain IKKβ IκB kinase β IL-12
interleukin 12 IP immunoprecipitation IRF interferon regulatory factor JNK Jun N-terminal …
interleukin 12 IP immunoprecipitation IRF interferon regulatory factor JNK Jun N-terminal …
Articles in PresS. Am J Physiol Heart Circ Physiol (April 21, 2006). doi: 10.1152/ajpheart. 01124.2005
Abstract Poly (ADP-ribose) polymerase-1 (PARP), a chromatin-bound enzyme is activated
by cell oxidative stress. Since oxidative-stress is also considered a main component of …
by cell oxidative stress. Since oxidative-stress is also considered a main component of …
[引用][C] Posttranslational modifications of Forkhead box O transcription factors
AA Horst - 2006 - Utrecht University
Beyond induction of histone acetylation: the multi-facets of the antineoplastic effect of HDAC inhibitors
CS Chen - 2006 - rave.ohiolink.edu
Histone deacetylase (HDAC) is recognized as one of the promising targets for cancer
therapy as aberrant transcriptional regulation of the epigenetic system has been linked to …
therapy as aberrant transcriptional regulation of the epigenetic system has been linked to …
[图书][B] Development of sirtuin and calmodulin-dependent protein kinase inhibitors as anti-cancer therapeutics
AD Schuler - 2006 - search.proquest.com
Small molecule inhibitors of the human sirtuins and calmodulin-dependent protein kinases
have shown promising anti-cancer activity in cell-based screens and animal models. We …
have shown promising anti-cancer activity in cell-based screens and animal models. We …
[PDF][PDF] Calories and longevity: do they really matter?
KJ Golden - Forum on Public Policy: A Journal of the Oxford Round …, 2006 - Citeseer
Calorie restriction extends the life span of laboratory animals, and now scientists are
beginning to discover the molecular basis for this phenomenon. The findings so far indicate …
beginning to discover the molecular basis for this phenomenon. The findings so far indicate …
[PDF][PDF] Die humanen Sir2-Orthologe SIRT1 und SIRT2 als Substrate Cyklin-abhängiger Kinasen
R Pandithage - 2006 - core.ac.uk
Das Protein SIRT2 ist eine NAD+-abhängige Deacetylase und eins von sieben humanen
Sirtuinen. Die Zugehörigkeit zur Sirtuin Familie wird über eine 200 bis 275 Aminosäuren …
Sirtuinen. Die Zugehörigkeit zur Sirtuin Familie wird über eine 200 bis 275 Aminosäuren …
[图书][B] The role of mammalian target of rapamycin (mTOR) in insulin resistance
A Tzatsos - 2006 - search.proquest.com
Nutritional excess and/or obesity represent well-known predisposition factors for the
development of non-insulin dependent diabetes mellitus (NIDDM). However, molecular links …
development of non-insulin dependent diabetes mellitus (NIDDM). However, molecular links …