As sensors for fat-soluble hormones and dietary lipids, oscillations in nuclear receptor (NR)
expression in key metabolic tissues may contribute to circadian entrainment of nutrient and …

As ligand-dependent transcription factors, the nuclear receptor superfamily governs a
remarkable array of rhythmic physiologic processes such as metabolism and reproduction …

Daily rhythms in behavior and physiology are observed in most organisms. These rhythms
are controlled by internal self-sustained circadian (∼ 24 h) clocks, which are present in …

Recent advances in the understanding of the molecular, genetic, neural, and physiologic
basis for the generation and organization of circadian clocks in mammals have revealed …

Background While additional research is needed, a number of large epidemiological studies
show an association between circadian disruption and metabolic disorders. Specifically …

In the last decades, obesity has been on the rise becoming a burden for health care
systems. The reasons behind this rise are most likely caused by lifestyle rather than by an …

The circadian clock programs daily rhythms and coordinates multiple behavioral and
physiological processes, including activity, sleep, feeding, and fuel homeostasis. Recent …

Circadian rhythms characterize almost every aspect of human physiology, endocrinology,
xenobiotic detoxification, cell growth, and behavior. Modern lifestyles that disrupt our normal …

Circadian rhythms are normal variations in physiological processes that occur over the
period of a day. These rhythms are essential for the organism since they allow anticipatory …

The endogenous circadian clock ensures daily rhythms in diverse behavioral and
physiological processes, including locomotor activity and sleep/wake cycles, but also food …