838 medication have significant differences with regard to their ancillary pharmacological
properties and thereby also their profile at a molecular/cellular level. Furthermore, these …

Angiotensin Receptor Blockers Do Not Reduce Risk of Myocardial Infarction,
Cardiovascular Death, or Total Mortality: Further Evidence for the ARB-MI Paradox …

Aims The uncertainty surrounding safety of angiotensin receptor blockers (ARBs) increased
after publication of experimental and clinical studies which suggested an excess risk of …

855 cause MI, 24 we were both intrigued and puzzled; intrigued because, like ACE
inhibitors, ARBs were expected to reduce MI, yet puzzled because they had only reported …

The renin–angiotensin system (RAS) plays key roles throughout the cardiovascular
continuum, and blockade of this system—either through angiotensin-converting enzyme …

In the prevention and treatment of cardiovascular disease, pharmacological treatment
strategies should have several aims:(i) in individuals without overt cardiovascular disease …

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Proven cardiovascular benefit from angiotensin-converting enzyme (ACE) inhibition is a
cornerstone of evidence-based medicine. The first study to show dramatic benefits from ACE …

Objective To evaluate the effect of angiotensin receptor blockers on the risk of myocardial
infarction in patients at risk for cardiovascular events. Design Systematic review of controlled …

Cardiovascular disease represents a continuum that starts with risk factors such as
hypertension and progresses to atherosclerosis, target organ damage, and ultimately to …