The aim was to determine the effect of fybrinolytic therapy by streptokinase on chemotherapy
and radiation response in human colon cancer cells. The cells were treated with different …

In the last few years increased release of fibrinolytic enzymes from malignant cells has been
observed, but the significance of this property in relation to malignant growth is still not fully …

To date, oxaliplatin and irinotecan are used in combination with 5-flourouracil (5-FU) for
metastatic colorectal cancer. In this study it was tested whether oxaliplatin and irinotecan …

Scirrhous gastric cancer is resistant to chemotherapy in comparison to other types of gastric
cancers, and cancer cell-stromal fibroblast interactions play an important role in progression …

It is possible that a strategy designed to stimulate cancer cells in the active cell cycle may
increase the effectiveness of S-phase specific anti-cancer agents such as methotrexate. In …

Background Fibroblasts have been reported to play an important role in the proliferation of
scirrhous gastric cancer cells. It would be an effective cancer therapy to reduce the cancer …

Background: The synergistic antitumor effect of a combination of docetaxel and capecitabine
is reported to be attributable to docetaxel-mediated up-regulation of thymidine …

Inhibitory effects and potential mechanisms of capecitabine metronomic chemotherapy on
colon cancer were investigated in this study. Metronomic chemotherapy with fluorouracil or …

Inhibition of protein synthesis can alter cellular responsiveness to the classical anticancer
drugs. The in vitro response of Chinese hamster ovary (CHO) cells to cisplatin with or …

Background: Glutathione has been implicated in growth factor-mediated chemoresistance of
colon cancer cells. Materials and Methods: We evaluated the influence of hepatocyte growth …