Fear extinction is the decrease in conditioned fear responses that normally occurs when a
conditioned stimulus (CS) is repeatedly presented in the absence of the aversive …

Clinical research has linked post-traumatic stress disorder (PTSD) with deficits in fear
extinction. However, it is not clear whether these deficits result from stress-related changes …

BACKGROUND: A clinical characteristic of posttraumatic stress disorder (PTSD) is
persistently elevated fear responses to stimuli associated with the traumatic event. The …

Understanding how fears are acquired is an important step in translating basic research to
the treatment of fear-related disorders. However, understanding how learned fears are …

Fear extinction does not prevent post-traumatic stress or have long-term therapeutic benefits
in fear-related disorders unless extinction memories are easily retrieved at later encounters …

Fear extinction, the reduction of fear by repeated exposure to the object of fear, is a crucial
paradigm of inhibitory learning and the acknowledged preclinical model for behavior …

BACKGROUND: Extinction of conditioned fear is thought to form a new safety memory that is
expressed in the context in which the extinction learning took place. Rodent studies …

Laboratory models of extinction learning in animals and humans have the potential to
illuminate methods for improving clinical treatment of fear-based clinical disorders. However …

Anxiety disorders are commonly treated with exposure-based therapies that rely on
extinction of conditioned fear. Persistent fear and anxiety following exposure therapy could …

Extinction training is a form of inhibitory learning that allows an organism to associate a
previously aversive cue with a new, safe outcome. Extinction does not erase a fear …