Background: TP53 is a gene and p53 is its product protein. Since its discovery many studies
have looked into its function and its role in cancer. It is not only involved in the induction of …

Mutations in the p53 tumour suppressor gene are probably the most common somatic or
acquired genetic abnormalities implicated in human malignant disease. Amongst the …

Breast tumors are thought to originate, grow, and metastasize in an environment which
includes steroid hormone receptors, their cognate steroid ligands, and many gene products …

This is a critical review of the biological basis of the p53 protein in apoptosis, it's importance
in the experimental and human carcinogenesis and the laboratory procedures used for it's …

p53 suppressor tumoral gene codifies the nuclear proteins which suppress the cellular
proliferation by preventing the entrance of the cells in the division cycle. The loss or …

This is a critica/review of the biologica/basis of the p53 protein in apoptosis, it's importance
in the experimental and human carcinogenesis and the laboratory procedures used for it's …

The p53 oncosuppressor gene has a negative influence on cell proliferation. Expression of
mutant p53 is frequently seen in breast tumors and has been significantly related with …

Breast cancer is the most common malignant tumour disease and also the main cause of
cancer-related deaths among women. The lifetime risk in western countries is 10%. The …

One hundred and eighty-one breast cancer specimens were analyzed for nuclear p53
staining by immunochemical methods. There were 123 fine-needle cytological specimens …