Temperature-sensitive hydrogels with SiO2–Au nanoshells for controlled drug delivery

M Bikram, AM Gobin, RE Whitmire, JL West - Journal of Controlled Release, 2007 - Elsevier
Silica–gold (SiO2–Au) nanoshells are a new class of nanoparticles that consist of a silica
dielectric core that is surrounded by a gold shell. These nanoshells are unique because …

Discrete thermally responsive hydrogel‐coated gold nanoparticles for use as drug‐delivery vehicles

JH Kim, T Randall Lee - Drug development research, 2006 - Wiley Online Library
This report describes the development of optically responsive gold nanoparticles (∼ 60 nm
in diameter) coated with a thermally responsive biocompatible hydrogel overlayer (20–90 …

Temperature‐sensitive polymer–nanoshell composites for photothermally modulated drug delivery

SR Sershen, SL Westcott, NJ Halas… - Journal of Biomedical …, 2000 - Wiley Online Library
Composites of thermally sensitive hydrogels and optically active nanoparticles have been
developed for the purpose of photothermally modulated drug delivery. Copolymers of N …

Hydrogel-coated near infrared absorbing nanoshells as light-responsive drug delivery vehicles

LE Strong, JL West - ACS Biomaterials Science & Engineering, 2015 - ACS Publications
Nanoparticle drug delivery carriers that can modulate drug release based on an exogenous
signal, such as light, are of great interest, especially for improving cancer therapy. A light …

Hydrogel-nanoparticle composites for optically modulated cancer therapeutic delivery

LE Strong, SN Dahotre, JL West - Journal of Controlled Release, 2014 - Elsevier
A poly (N-isopropylacrylamide-co-acrylamide)(NIPAAm-co-AAm) hydrogel with near-infrared
(NIR) absorbing silica–gold nanoshells was designed as a platform for pulsatile delivery of …

Development of a temperature‐sensitive composite hydrogel for drug delivery applications

RMK Ramanan, P Chellamuthu, L Tang… - Biotechnology …, 2006 - Wiley Online Library
To develop materials with improved controllability and specificity, we have investigated
composite hydrogels with temperature‐sensitive properties using photo cross‐linking …

Preparation of thermo-responsive and injectable hydrogels based on hyaluronic acid and poly(N-isopropylacrylamide) and their drug release behaviors

DI Ha, SB Lee, MS Chong, YM Lee, SY Kim… - Macromolecular …, 2006 - Springer
Copolymers composed of hyaluronic acid (HA) and poly (N-isopropylacrylamide)(PNIPAAm)
were prepared to create temperature-sensitive injectable gels for use in controlled drug …

Role of thermo-responsiveness and poly (ethylene glycol) diacrylate cross-link density on protein release from poly (N-isopropylacrylamide) hydrogels

PW Drapala, EM Brey, WF Mieler… - Journal of …, 2011 - Taylor & Francis
Thermo-responsive hydrogels have shown promise as injectable materials for local drug
delivery. However, the phase-induced changes in polymer properties of N …

Thermo-and pH-responsive hydrogel-coated gold nanoparticles

JH Kim, TR Lee - Chemistry of materials, 2004 - ACS Publications
This article describes the structural and optical properties of a new class of hybrid
nanoparticles that consists of a small gold core (∼ 60 nm in diameter) coated with a …

Swelling and diffusion characteristics of modified poly (N-isopropylacrylamide) hydrogels

G Fu, WO Soboyejo - Materials Science and Engineering: C, 2010 - Elsevier
Thermo-responsive hydrogels are capable of swelling changes to external temperature. A
series of modified poly (N-isopropylacrylamide)(PNIPA) hydrogels was synthesized by free …