AIM: To establish the effects of Na+/Ca2+ exchanger (NCX) blockers on 2-[18F] fluoro-2-
deoxy-d-glucose (18FDG) and 11C-choline accumulation in different cancer cells …

After observing that fluorine-18 fluorodeoxyglucose positron emission tomography (18F-
FDG-PET) is not sensitive enough in this field, in 1998, Hara et al.[2] introduced 11C-choline …

Purpose: We elucidated the utilization of [18F]-Fluor-deoxy-glucose (FDG) and [18F]-Fluor-
methyl-choline (FMC) as imaging biomarkers for the T24 bladder cancer cell line for therapy …

One purpose of the study was to explore the PET tracer 11C-L-DOPA for the discrimination
between small-cell lung cancer (SCLC) and non small-cell lung cancer (NSCLC). A further …

INTRODUCTION: Choline, acetate and glucose ([2-18F] fluoro-2-deoxyglucose,[18F] FDG)
analogs are under investigation as positron emission tomography (PET) tracers for the …

Results We found abnormal uptake of the tracer, not related to PC, in 48/300 patients (16%).
Most of these findings were due to inflammatory processes. Furthermore, some malignant …

Capillary endothelial cells in the brain express P-glycoprotein (P-gp), which works as a
functional blood-brain barrier (BBB). P-gp pumps out multiple types of molecules from the …

Furosemide, a blocker of Na+/K+/2Cl–cotransporter (NKCC), is often used as a diuretic to
improve edema, ascites, and pleural effusion of patients with cancers. The aim of the present …

Our aim was to determine whether the Ca 2+ ion or cell membrane Ca 2+ and Na+/Ca 2+
ion transport systems are involved in maintaining the cell-associated activity of technetium …

Purpose Choline derivatives labelled with positron emitters are successfully used for PET
imaging of prostate cancer patients. Since little is known about uptake mechanisms, the aim …