Aldosterone and angiotensin II (ANG II) contribute to the development and progression of
renal damage. Here we investigated the effects of bone morphogenetic proteins (BMPs) on …

Aldosterone production is modified by several growth factors that reside in the adrenal. We
have recently reported the existence of a bone morphogenetic protein (BMP) system in …

Bone morphogenetic protein (BMP)-7 exerts dose-dependent stimulatory and inhibitory
effects during renal branching morphogenesis. Previously, we identified an inhibitory role for …

Abstract Background Bone Morphogenetic Protein (BMP)-7 is protective in different animal
models of acute and chronic kidney disease. Its role in human kidneys, and in particular …

Several clinical and experimental data support the hypothesis that aldosterone contributes
to the progression of renal injury. To determine the signaling pathway of aldosterone in …

In vivo studies have demonstrated that aldosterone is an independent contributor to
glomerulosclerosis. In the present study, we have investigated whether aldosterone itself …

Accumulating evidence demonstrates that aldosterone can cause extra-cellular matrix
(ECM) accumulation, in addition to regulating sodium and potassium homeostasis …

Here we investigated the effects of mineralocorticoid in the regulation of catecholamine
biosynthesis using rat pheochromocytoma PC12 cells. Expression of mineralocorticoid …

Adult renal progenitor cells (ARPCs) isolated from the human kidney may contribute to
repair featuring acute kidney injury (AKI). Bone morphogenetic proteins (BMPs) regulate …

Background/Aims: The mineralocorticoid hormone, aldosterone, has pro-fibrotic properties
which can cause kidney damage. The severity of kidney interstitial fibrosis is dependent on …