Context: In primary aldosteronism, elevated serum 18-hydroxycorticosterone (18OHB)
suggests aldosterone-producing adenoma (APA) rather than bilateral, idiopathic …

Abstract Context: 18-Oxocortisol (18-oxoF) is a derivative of cortisol (F) that is produced by
aldosterone synthase (CYP11B2). The potential for this steroid as a biomarker for …

Context: Diagnosis of primary aldosteronism (PA) is made by screening, confirmation
testing, and subtype diagnosis (computed tomography scan and adrenal vein sampling) …

BACKGROUND Differentiating patients with primary aldosteronism caused by aldosterone-
producing adenomas (APAs) from those with bilateral adrenal hyperplasia (BAH), which is …

Adrenal venous sampling is currently the only reliable method to distinguish unilateral from
bilateral diseases in primary aldosteronism. In this study, we attempted to determine whether …

Context Previous studies suggested that plasma aldosterone (PAC) response to ACTH
stimulation could predict the subtypes of primary aldosteronism (PA) and avoid adrenal …

Context: Adrenal vein sampling (AVS) is required to identify a lateralized or bilateral
aldosterone source in primary aldosteronism. Objectives: Our objectives were to compare …

Background Steroid profiling for diagnosis of endocrine disorders featuring disordered
production of steroid hormones is now possible from advances in liquid chromatography …

Abstract Objective Urine 18-hydroxycortisol (18-OHF) measurements are claimed to
discriminate between primary hyperaldosteronism due to Conn's syndrome/adrenal …

Purpose To assess the sensitivity and specificity for ratios of adrenal vein cortisol level (C a)
to peripheral vein cortisol level (C p), adrenal vein aldosterone level (A a) to peripheral vein …