Regulators of G-protein signaling 4 in adrenal gland: localization, regulation, and role in aldosterone secretion
DG Romero, MY Zhou, LL Yanes… - Journal of …, 2007 - joe.bioscientifica.com
Regulators of G-protein signaling (RGS proteins) interact with Gα subunits of heterotrimeric
G-proteins, accelerating the rate of GTP hydrolysis and finalizing the intracellular signaling …
G-proteins, accelerating the rate of GTP hydrolysis and finalizing the intracellular signaling …
RGS2 is regulated by angiotensin II and functions as a negative feedback of aldosterone production in H295R human adrenocortical cells
DG Romero, MW Plonczynski… - …, 2006 - academic.oup.com
Regulator of G protein signaling (RGS) proteins interact with Gα-subunits of heterotrimeric G
proteins, accelerating the rate of GTP hydrolysis and finalizing the intracellular signaling …
proteins, accelerating the rate of GTP hydrolysis and finalizing the intracellular signaling …
RGS proteins and cardiovascular Angiotensin II Signaling: Novel opportunities for therapeutic targeting
A Lymperopoulos, JI Borges, RA Stoicovy - Biochemical Pharmacology, 2023 - Elsevier
Angiotensin II (AngII), as an octapeptide hormone normally ionized at physiological pH,
cannot cross cell membranes and thus, relies on, two (mainly) G protein-coupled receptor …
cannot cross cell membranes and thus, relies on, two (mainly) G protein-coupled receptor …
Potential role for a regulator of G protein signaling (RGS3) in gonadotropin-releasing hormone (GnRH) stimulated desensitization
JD Neill, LW Duck, JC Sellers, LC Musgrove… - …, 1997 - academic.oup.com
The cellular and molecular mechanisms of gonadotrope desensitization are unknown but
transduction of the GnRH signal is known to involve sequentially the GnRH receptor, Gqα …
transduction of the GnRH signal is known to involve sequentially the GnRH receptor, Gqα …
A regulator of G protein signaling, RGS3, inhibits gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) secretion
Background Luteinizing hormone secreted by the anterior pituitary gland regulates gonadal
function. Luteinizing hormone secretion is regulated both by alterations in gonadotrope …
function. Luteinizing hormone secretion is regulated both by alterations in gonadotrope …
Selective inhibition of α1A-adrenergic receptor signaling by RGS2 association with the receptor third intracellular loop
C Hague, LS Bernstein, S Ramineni, Z Chen… - Journal of Biological …, 2005 - ASBMB
Regulators of G-protein signaling (RGS) proteins act directly on Gα subunits to increase the
rate of GTP hydrolysis and to terminate signaling. However, the mechanisms involved in …
rate of GTP hydrolysis and to terminate signaling. However, the mechanisms involved in …
Cardiotonic steroids stabilize regulator of G protein signaling 2 protein levels
B Sjögren, S Parra, LJ Heath, KB Atkins, ZJ Xie… - Molecular …, 2012 - ASPET
Regulator of G protein signaling 2 (RGS2), a Gq-specific GTPase-activating protein, is
strongly implicated in cardiovascular function. RGS2 (−/−) mice are hypertensive and prone …
strongly implicated in cardiovascular function. RGS2 (−/−) mice are hypertensive and prone …
Regulation of RGS3 and RGS10 palmitoylation by GnRH
C Castro-Fernández, JA Janovick, SP Brothers… - …, 2002 - academic.oup.com
Regulators of G protein signaling (RGS) play a pivotal role in cellular signal transduction.
RGS3 or RGS10 were overexpressed in GGH3 cells [GH3 cells stably expressing the GnRH …
RGS3 or RGS10 were overexpressed in GGH3 cells [GH3 cells stably expressing the GnRH …
Characterization of RGS5 in regulation of G protein-coupled receptor signaling
RGS proteins (regulators of G protein signaling) serve as GTPase-activating proteins (GAPs)
for Gα subunits and negatively regulate G protein-coupled receptor signaling. In this study …
for Gα subunits and negatively regulate G protein-coupled receptor signaling. In this study …
Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions
AA Roy, KE Lemberg, P Chidiac - Molecular pharmacology, 2003 - ASPET
N-terminally green fluorescent protein (GFP)-tagged regulator of G protein signaling (RGS) 2
and RGS4 fusion proteins expressed in human embryonic kidney 293 cells localized to the …
and RGS4 fusion proteins expressed in human embryonic kidney 293 cells localized to the …