Anaplastic large-cell lymphoma (ALCL) frequently carries the t (2; 5)(p23; q35), resulting in
aberrant expression of nucleophosmin-anaplastic lymphoma kinase (NPM-ALK). We show …

Most of the anaplastic large-cell lymphoma (ALCL) cases carry the t (2; 5; p23; q35) that
produces the fusion protein NPM-ALK (nucleophosmin-anaplastic lymphoma kinase). NPM …

More than half of anaplastic large-cell lymphomas (ALCLs) have a chromosomal
translocation t (2; 5) that leads to the expression of a hybrid protein composed of the …

Anaplastic large cell lymphomas (ALCLs) are frequently associated with the t (2; 5)(p23;
q35) translocation, leading to the expression of NPM-ALK, a fusion protein linking …

The fusion protein, nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), results from
the chromosome translocation t (2; 5)(p23; q25) and is present in 50–70 percent of …

Anaplastic large cell lymphoma (ALCL) is characterized by the presence of the t (2; 5)(p23;
q35) generating the nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) fusion protein …

Anaplastic large-cell lymphomas (ALCLs) are lymphomas of T or null phenotype often
associated with a chromosomal translocation, t (2; 5)(p23; q35). This translocation leads to …

Constitutive overexpression of nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) is a
key oncogenic event in anaplastic large-cell lymphomas with the characteristic …

NPM/ALK is an oncogenic fusion protein expressed in∼ 50% of anaplastic large cell
lymphoma cases. It derives from the t (2; 5)(p23; q35) chromosomal translocation that fuses …

Anaplastic large-cell lymphoma is a subtype of non-Hodgkin lymphomas characterized by
the expression of CD30. More than half of these lymphomas carry a chromosomal …