Clinical Pharmacology is commonly accepted to be a bridging discipline between basic
science observations and clinical practice. Today, it should be a major task of the clinical …

Healing after myocardial infarction (MI) is a well-orchestrated time-dependent process that
involves inflammation, tissue repair with extracellular collagen matrix (ECCM) deposition …

Abstract Purpose Angiotensin receptor blockers (ARBs) offer a new treatment alternative for
patients with hypertension and heart failure. Due to comparatively high prices, most …

Atrial fibrillation (AF) is the most common disorder of cardiac rhythm and is responsible for
substantial morbidity and mortality in general population. A recent community-based …

The role of angiotensin-receptor blockers in primary or secondary prevention of
cardiovascular disease has been unclear. Speculation about equivalence to …

Renal dysfunction is a frequent and progressive complication of chronic heart failure and is
a powerful predictor of cardiovascular mortality. It is intimately associated with …

Although considerable progress has been made in the pharmacologic and device
management of chronic heart failure in recent decades, heart failure patients continue to …

Background: In patients with heart failure and reduced left ventricular ejection fraction,
angiotensin receptor blockers have been found to reduce mortality and morbidity and to …

Chronic heart failure (HF) is a major cause of morbidity and mortality particularly in the
elderly and a growing healthcare burden in Italy. The objective was to assess the cost …