The role of the renin-angiotensin-aldosterone system (RAAS) in many cardiovascular
disorders, including hypertension, cardiac hypertrophy, and atherosclerosis, is well …

The renin–angiotensin aldosterone system (RAAS) is central to the pathogenesis of
cardiovascular disease. RAAS inhibition can reduce blood pressure, prevent target organ …

Atrial arrhythmias, ventricular arrhythmias, and sudden cardiac death (SCD) are significant
health problems and an economic burden to society. The renin‐angiotensin‐aldosterone …

BACKGROUND: The renin-angiotensin aldosterone system (RAAS) is a hormonal cascade
that functions in the homeostatic control of arterial pressure, tissue perfusion, and …

The renin-angiotensin-aldosterone system (RAAS) plays a significant role in the
pathophysiology of multiple disease states. Its activation leads to vasoconstriction, vascular …

Atrial fibrillation (AF) represents the most common sustained cardiac arrhythmia, as it affects
1%–2% of the general population and up to 15% of people over 80 years. High blood …

Activation of the renin–angiotensin–aldosterone system (RAAS) results in vasoconstriction,
muscular (vascular and cardiac) hypertrophy and fibrosis. Established arterial stiffness and …

Inhibition of the renin-angiotensin-aldosterone system is a novel concept for the treatment of
atrial fibrillation that may target the underlying substrate of atrial fibrillation. Further human …

The renin-angiotensin-aldosterone system (RAAS) plays an integral role in maintaining
vascular tone, optimal salt and water homeostasis, and cardiac function in humans …

Atrial fibrillation (AF) is the most prevalent arrhythmia and its incidence is on the rise. AF
causes significant morbidity and mortality leading to rising AF-related health care costs …