M Böhm - The American journal of cardiology, 2007 - Elsevier
Cardiovascular disease represents a continuum that starts with risk factors, such as hypertension, and progresses to atherosclerosis, target organ damage, and ultimately leads …
E Lonn - Current Atherosclerosis Reports, 2002 - Springer
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) effectively interfere with the renin-angiotensin system and exert various beneficial actions on …
MA Weber, TD Giles - Reviews in cardiovascular medicine, 2006 - europepmc.org
The renin-angiotensin system (RAS) plays a pivotal role in the progression of some forms of hypertension and cardiovascular disease. The development of angiotensin-converting …
BI Lévy, JJ Mourad - American Journal of Hypertension, 2022 - academic.oup.com
Despite a similar beneficial effect on blood pressure lowering observed with angiotensin- converting enzyme inhibitors (ACEIs) and angiotensin II type 1 receptor (AT1R) blocker …
J Martin, H Krum - Pharmacological research, 2002 - Elsevier
Blockade of the renin–angiotensin system by angiotensin converting enzyme (ACE) inhibitors reduces mortality and morbidity in patients post-myocardial infarction as well as in …
OBJECTIVE: To determine, through a review of the medical literature, whether there is adequate evidence to support the use of angiotensin receptor blockers (ARBs) in place of …
A Pourdjabbar, N Lapointe… - The Canadian journal of …, 2002 - europepmc.org
Angiotensin receptor blockers (ARBs) were developed to better antagonize the effects of chronic overactivation of angiotensin II. In clinical studies, ARBs have consistently been …
AP Maggioni - Cardiovascular drugs and therapy, 2006 - Springer
The cardiovascular continuum describes the progression of pathophysiologic events from cardiovascular risk factors to symptomatic cardiovascular disease (CVD) and life-threatening …
F Ruschitzka, S Taddei - European heart journal, 2012 - academic.oup.com
The renin-angiotensin-aldosterone system (RAAS) is essential for the regulation of blood pressure, cardiovascular and renal function. Drugs inhibiting the RAAS, particularly …