RAS blockade with ARB and ACE inhibitors: current perspective on rationale and patient selection

C Werner, M Baumhäkel, KK Teo, R Schmieder… - Clinical Research in …, 2008 - Springer
Cardiovascular disease represents a continuum that starts with risk factors such as
hypertension and progresses to atherosclerosis, target organ damage, and ultimately to …

Angiotensin receptor blockers versus angiotensin-converting enzyme inhibitors: where do we stand now?

M Böhm - The American journal of cardiology, 2007 - Elsevier
Cardiovascular disease represents a continuum that starts with risk factors, such as
hypertension, and progresses to atherosclerosis, target organ damage, and ultimately leads …

Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in atherosclerosis

E Lonn - Current Atherosclerosis Reports, 2002 - Springer
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs)
effectively interfere with the renin-angiotensin system and exert various beneficial actions on …

Inhibiting the renin-angiotensin system to prevent cardiovascular diseases: do we need a more comprehensive strategy?

MA Weber, TD Giles - Reviews in cardiovascular medicine, 2006 - europepmc.org
The renin-angiotensin system (RAS) plays a pivotal role in the progression of some forms of
hypertension and cardiovascular disease. The development of angiotensin-converting …

Renin angiotensin blockers and cardiac protection: from basics to clinical trials

BI Lévy, JJ Mourad - American Journal of Hypertension, 2022 - academic.oup.com
Despite a similar beneficial effect on blood pressure lowering observed with angiotensin-
converting enzyme inhibitors (ACEIs) and angiotensin II type 1 receptor (AT1R) blocker …

Role of valsartan and other angiotensin receptor blocking agents in the management of cardiovascular disease

J Martin, H Krum - Pharmacological research, 2002 - Elsevier
Blockade of the renin–angiotensin system by angiotensin converting enzyme (ACE)
inhibitors reduces mortality and morbidity in patients post-myocardial infarction as well as in …

Angiotensin receptor blockers versus ACE inhibitors: prevention of death and myocardial infarction in high-risk populations

BJ Epstein, JG Gums - Annals of Pharmacotherapy, 2005 - journals.sagepub.com
OBJECTIVE: To determine, through a review of the medical literature, whether there is
adequate evidence to support the use of angiotensin receptor blockers (ARBs) in place of …

Angiotensin receptor blockers: Powerful evidence with cardiovascular outcomes?

A Pourdjabbar, N Lapointe… - The Canadian journal of …, 2002 - europepmc.org
Angiotensin receptor blockers (ARBs) were developed to better antagonize the effects of
chronic overactivation of angiotensin II. In clinical studies, ARBs have consistently been …

Efficacy of angiotensin receptor blockers in cardiovascular disease

AP Maggioni - Cardiovascular drugs and therapy, 2006 - Springer
The cardiovascular continuum describes the progression of pathophysiologic events from
cardiovascular risk factors to symptomatic cardiovascular disease (CVD) and life-threatening …

Angiotensin-converting enzyme inhibitors: first-line agents in cardiovascular protection?

F Ruschitzka, S Taddei - European heart journal, 2012 - academic.oup.com
The renin-angiotensin-aldosterone system (RAAS) is essential for the regulation of blood
pressure, cardiovascular and renal function. Drugs inhibiting the RAAS, particularly …