Post translational modification (PTM) of histones has long been associated with epigenetic
regulation. Although genomic approaches have established correlation between a handful …

Modern techniques in molecular biology, genomics, and mass spectrometry–based
proteomics have identified a large number of novel histone posttranslational modifications …

Histone post-translational modifications (PTMs) positively and negatively regulate gene
expression, and are consequently a vital influence on the genomic profile of all eukaryotic …

Histone post-translational modifications (PTMs) have been linked to a variety of biological
processes and disease states, thus making their characterization a critical field of study. In …

Histone proteins are dynamically modified to mediate a variety of cellular processes
including gene transcription, DNA damage repair, and apoptosis. Regulation of these …

Histones are the primary protein component of chromatin and are involved in virtually all
DNA‐templated processes. Histones are abundantly post‐translationally modified by a …

Histone post-translational modifications (PTMs) comprise one of the most intricate nuclear
signaling networks that govern gene expression in a long-term and dynamic fashion. These …

Chromatin is the macromolecular nucleoprotein complex that governs the organization of
genetic material in the nucleus of eukaryotic cells. In chromatin, DNA is packed with histone …

Epigenetic modifications contribute to the determination of cell fate and differentiation. The
molecular mechanisms underlying histone variants and post-translational modifications …

Functional epigenetic regulation occurs by dynamic modification of chromatin, including
genetic material (ie, DNA methylation), histone proteins, and other nuclear proteins. Due to …