Nod2 es un receptor de reconocimiento de patrones (PRR) citoplásmico, perteneciente a la
familia de receptores de tipo NOD (NLR) y consta de tres tipos de dominios estructurales y …

Nod2 es un receptor de reconocimiento de patrones (PRR) citoplásmico, perteneciente a la
familia de receptores de tipo NOD (NLR) y consta de tres tipos de dominios estructurales y …

We wished to analyse the frequency of Crohn's disease-linked CARD15 polymorphisms
(P268S, R702W, G908R and 1007fs) in a group of Spanish patients with idiopathic uveitis …

Uveitis is a clinical feature of the Blau syndrome, a disease linked to CARD15 (also referred
to as NOD2) mutations. Three main mutations in this gene (R334W, R334Q and L469F) …

Purpose: CARD15 is a gene that has recently been identified as a Crohn's disease
susceptibility gene at the IBD1 locus, and is the gene responsible for familial juvenile …

Abstract Background The etiology of Autoimmune chronic uveitis (ACU) is still unknown;
NOD2/CARD15 gene mutations are responsible for the Blau Syndrome and can induce …

Purpose: CARD15/NOD2 mutations have been found to cause a rare autosomal–dominant
form of uveitis called familial juvenile systemic granulomatosis (also called Blau syndrome …

Purpose: Mutations in CARD15 (IBD1, NOD2) are responsible for a rare, autosomal-
dominant syndrome: familial juvenile systemic granulomatosis (Blau syndrome). This …

CARD15 was first identified as a susceptibility gene for Crohn's disease. More recently,
CARD15 mutations were shown to be associated with the pediatric granulomatous …

Objectives Aim of our study is to assess if NOD2-polymorphisms or mutations have a role in
the etiology or in the clinical course of patients with non infectious uveitis, either idiopathic or …