It is evident that metabolic memory, whereby diabetic complications continue to develop and
progress in individuals who returned to normal glycemic control after a period of transient …

The intestinal epithelium maintains a state of controlled inflammation despite continuous
contact with Gram-negative commensal bacteria and lipopolysaccharide (LPS) on its luminal …

Histone acetyl transferases (HATs) play a crucial role in eukaryotes by regulating chromatin
architecture and locus-specific transcription. The GCN5 HAT was identified as a subunit of …

Candida biofilms are resistant to a range of antifungal agents in current clinical use. The
basis of this drug resistance is not clear, but in some cases it could be due to the presence of …

Parasitic protozoa such as the apicomplexan Toxoplasma gondii progress through their life
cycle in response to stimuli in the environment or host organism. Very little is known about …

The state of modification of histone tails plays an important role in defining the accessibility
of DNA for the transcription machinery and other regulatory factors. It has been extensively …

Chondrocyte differentiation is the fundamental process in skeletal development. From the
mesenchymal condensation of chondroprogenitors to the hypertrophic maturation of …

MORIMOTO T et al. cAMP-responsible transcription factor CBP. 6, 7 The primary structure of
p300 resembles that of CBP, 8 and both these proteins possess the KIX domain …

Androgen receptor (AR)-mediated gene regulation involves interactions with coregulatory
proteins that include the melanoma antigen gene protein-A11 (MAGE-11). To understand …

The human protein Nα‐terminal acetyltransferase A complex (hNatA), composed of the
catalytic hNaa10p (hArd1) and auxiliary hNaa15p (hNat1/NATH/Tubedown) subunits, was …