AIMS: The present study aimed to assess the effects of excess fat, fructose and fat-plus-
fructose intakes on intrahepatocellular lipid (IHCL). METHODS: Healthy male subjects were …

Objective: To assess how intrahepatic fat and insulin resistance relate to daily fructose and
energy intake during short‐term overfeeding in healthy subjects. Design and methods: The …

Background: High fructose consumption is suspected to be causally linked to the epidemics
of obesity and metabolic disorders. In rodents, fructose leads to insulin resistance and …

Background & Aims Diets high in fructose have been proposed to contribute to nonalcoholic
fatty liver disease. We compared the effects of high-fructose and matched glucose intake on …

Context: Consumption of high-fructose diets promotes hepatic fatty acid synthesis (de novo
lipogenesis [DNL]) and an atherogenic lipid profile. It is unclear whether these effects occur …

An increasing amount of fructose in the diet is suggested to play a causal role in the
pathogenesis of the metabolic syndrome, type 2 diabetes and fatty liver. Our aim was to …

Background: Both nutritional and genetic factors are involved in the pathogenesis of
nonalcoholic fatty liver disease and insulin resistance. Objective: The aim was to assess the …

Background: About 9% of average dietary energy intake in the United States comes from
fructose. Such a high consumption raises concern about the metabolic effects of this sugar …

Excess fructose intake causes hypertriglyceridemia and hepatic insulin resistance in
sedentary humans. Since exercise improves insulin sensitivity in insulin-resistant patients …

Abstract Context: The American Heart Association Nutrition Committee recommends women
and men consume no more than 100 and 150 kcal of added sugar per day, respectively …