The TIP60 tumor suppressor is a histone acetyltransferase involved in transcriptional
regulation, checkpoint activation, and p53-directed proapoptotic pathways. We report that …

Tat-interacting protein of 60 kDa (TIP60) is an essential lysine acetyltransferase implicated
in transcription, DNA damage response and apoptosis. TIP60 protein expression is reduced …

The histone acetyl transferase Tip60 (HTATIP) belongs to a multimolecular complex
involved in the cellular response to DNA damage. Tip60 participates in cell cycle arrest …

The life cycle of human papillomaviruses (HPVs) is dependent upon differentiation of the
infected host epithelial cell as well as activation of the ataxia telangiectasia mutated (ATM) …

The histone acetyl transferase Tip60 (HTATIP) shares many properties with the tumor
suppressor p53 (TP53). Both proteins are involved in the cellular response to DNA damage …

TIP60 was originally identified as a cellular acetyltransferase protein that interacts with HIV-1
Tat. As a consequence, the role of TIP60 in transcriptional regulation has been investigated …

Tip60 is an essential acetyltransferase required for acetylation of nucleosomal histones and
other nonhistone proteins. Tip60 acetylates the p53 tumor suppressor at lysine 120 (K120) …

The Tip60 histone acetyltransferase is part of an evolutionarily conserved multisubunit
complex, NuA4, which is recruited by many transcription factors to their target promoters …

Acetylation is a prominent post-translational modification of nucleosomal histone N-terminal
tails, which regulates chromatin accessibility. Accordingly, histone acetyltransferases (HATs) …

Binding of high risk human papillomavirus (HPV) E6 protein to E6-associated protein
(E6AP), a cellular ubiquitin-protein ligase, enables E6AP to ubiquitinate p53, leading to p53 …